Genetics and pathophysiology of mitral valve prolapse

C Delwarde, R Capoulade, J Mérot… - Frontiers in …, 2023 - frontiersin.org
Mitral valve prolapse (MVP) is a common condition affecting 2–3% of the general
population, and the most complex form of valve pathology, with a complication rate up to 10 …

Replacement myocardial fibrosis in patients with mitral valve prolapse: relation to mitral regurgitation, ventricular remodeling, and arrhythmia

AL Constant Dit Beaufils, O Huttin, A Jobbe-Duval… - Circulation, 2021 - Am Heart Assoc
Background: Mitral valve prolapse (MVP) is a frequent disease that can be complicated by
mitral regurgitation (MR), heart failure, arterial embolism, rhythm disorders, and death. Left …

Left ventricular remodeling in non-syndromic mitral valve prolapse: volume overload or concomitant cardiomyopathy?

LL Pype, PB Bertrand, BP Paelinck… - Frontiers in …, 2022 - frontiersin.org
Mitral valve prolapse (MVP) is a common valvular disorder that can be associated with mitral
regurgitation (MR), heart failure, ventricular arrhythmias and sudden cardiac death. Given …

Myocardial fibrosis at cardiac MRI helps predict adverse clinical outcome in patients with mitral valve prolapse

S Figliozzi, G Georgiopoulos, PM Lopes, KB Bauer… - Radiology, 2023 - pubs.rsna.org
Background Patients with mitral valve prolapse (MVP) may develop adverse outcomes even
in the absence of mitral regurgitation or left ventricular (LV) dysfunction. Purpose To …

Comparison of mitral regurgitant volume assessment between proximal flow convergence and volumetric methods in patients with significant primary mitral …

A Altes, F Levy, L Iacuzio, H Dumortier… - Journal of the American …, 2022 - Elsevier
Background Discrepancies have been observed between transthoracic echocardiography
(TTE) and cardiac magnetic resonance imaging (CMR) severity grading in primary mitral …

Primary Atriopathy in Mitral Valve Prolapse: Echocardiographic Evidence and Clinical Implications

L Tastet, LJ Lim, D Bibby, G Hu, L Cristin… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Prominent multi-scallop systolic leaflet displacement toward the left atrium
(atrialization) is typically observed in bileaflet mitral valve prolapse (MVP) with mitral annular …

Floppy mitral valve/mitral valve prolapse and sudden cardiac death

KD Boudoulas, A Pitsis, F Triposkiadis, Y Han… - Progress in …, 2022 - Elsevier
It is well appreciated today that sudden cardiac death (SCD) occurs in patients with floppy
mitral valve (FMV)/mitral valve prolapse (MVP) without significant mitral regurgitation. Data …

Prevalence and clinical implications of tricuspid valve prolapse based on magnetic resonance diagnostic criteria

AC Guta, KC El-Tallawi, DT Nguyen, F Qamar… - Journal of the American …, 2023 - jacc.org
Background Tricuspid valve prolapse (TVP) is an uncertain diagnosis with unknown clinical
significance because of a scarcity of published data. Objectives In this study, cardiac …

[PDF][PDF] Machine Learning–Based Phenogrouping in Mitral Valve Prolapse Identifies Profiles Associated With Myocardial Fibrosis and Cardiovascular Events

O Huttin, N Girerd, A Jobbe-Duval… - J Am Coll Cardiol …, 2023 - researchgate.net
ABSTRACT BACKGROUND Structural changes and myocardial fibrosis quantification by
cardiac imaging have become increasingly important to predict cardiovascular events in …

[HTML][HTML] Dark-blood late gadolinium enhancement CMR improves detection of papillary muscle fibrosis in patients with mitral valve prolapse

CM Van De Heyning, RJ Holtackers, MS Nazir… - European Journal of …, 2022 - Elsevier
Purpose Papillary muscle fibrosis may act as an arrhythmogenic substrate in patients with
mitral valve prolapse (MVP). Previous studies used conventional bright-blood late …