Breast cancer exhibits various epigenetic abnormalities that regulate gene expression and
contribute to tumor characteristics. Epigenetic alterations play a significant role in cancer …

Breast cancer is the second leading cause of cancer-related death in women and is a
complex disease with high intratumoral and intertumoral heterogeneity. Such heterogeneity …

Objective Breast cancer (BC) is a multifactorial disease and is one of the most common
cancers globally. This study aimed to compare different machine learning (ML) techniques to …

Breast cancer is known as a most prevalent cancer and second deadly cancer, among
women worldwide. Due to the high incidence rate of breast cancer and limitations of …

Breast cancer is among the most important causes of cancer related death in women. There
is a need for novel agents for targeting key signaling pathways to either improve the efficacy …

Breast cancer is an important cause of cancer related mortality in women. Despite extensive
efforts to identify valid biomarkers for risk stratification, there are relatively few with proven …

Background Tamoxifen is a widely used estrogen receptor inhibitor, whose clinical success
is limited by the development of acquired resistance. This compound was also found to …

The E‐cadherin protein (Cadherin 1, gene: CDH1), a master regulator of the human
epithelial homeostasis, contributes to the epithelial‐mesenchymal transition (EMT) which …

Background: Cervical cancer is one of the most prevalent gynecologic cancers associated
with high morbidity and mortality worldwide. There is mounting evidence indicating an …

Abstract The 5, 10‐Methylenetetrahydrofolate reductase (MTHFR) was the rate‐limiting
enzyme in the methyl cycle, which was encoded by the MTHFR gene. MTHFR played a key …