Liposomes: Advancements and innovation in the manufacturing process
Liposomes are well recognised as effective drug delivery systems, with a range of products
approved, including follow on generic products. Current manufacturing processes used to …
approved, including follow on generic products. Current manufacturing processes used to …
Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness.
The disease has conventionally been characterized by an elevated intraocular pressure …
The disease has conventionally been characterized by an elevated intraocular pressure …
Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation
Acetazolamide (ACZ), a carbonic anhydrase inhibitor, is employed to decrease the
intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low aqueous …
intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low aqueous …
Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation
It was found that propranolol hydrochloride (PNL), which is a beta-blocker used for
hypertension treatment, has a potent spermicidal activity through local anesthetic activity or …
hypertension treatment, has a potent spermicidal activity through local anesthetic activity or …
Trans-corneal drug delivery strategies in the treatment of ocular diseases
L Li, F Jia, Y Wang, J Liu, Y Tian, X Sun, Y Lei… - Advanced Drug Delivery …, 2023 - Elsevier
The cornea is a remarkable tissue that possesses specialized structures designed to
safeguard the eye against foreign objects. However, its unique properties also make it …
safeguard the eye against foreign objects. However, its unique properties also make it …
Formulation and characterization of sertaconazole nitrate mucoadhesive liposomes for vaginal candidiasis
Purpose The aim of this study is to develop efficient localized therapy of sertaconazole
nitrate for the treatment of vaginal candidiasis. Methods Sertaconazole nitrate-loaded …
nitrate for the treatment of vaginal candidiasis. Methods Sertaconazole nitrate-loaded …
Tailoring terpesomes and leciplex for the effective ocular conveyance of moxifloxacin hydrochloride (Comparative assessment): in-vitro, ex-vivo, and in-vivo evaluation
Aim To compare the ability of both terpesomes (TPs) and leciplex (LPs) loaded moxifloxacin
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …
Fabrication of betaxolol hydrochloride-loaded highly permeable ocular bilosomes (HPOBs) to combat glaucoma: In vitro, ex vivo & in vivo characterizations
Betaxolol hydrochloride is a water-soluble antiglaucoma drug suffering from poor ocular
bioavailability necessitating frequent dosing that impede patient adherence to treatment …
bioavailability necessitating frequent dosing that impede patient adherence to treatment …
Formulation and optimization of cationic nanoemulsions for enhanced ocular delivery of dorzolamide hydrochloride using Box-Behnken design: In vitro and in vivo …
The present study was designed to develop dorzolamide HCl (DRZ) loaded cationic
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …
nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing high …
[HTML][HTML] Sertaconazole-nitrate-loaded leciplex for treating keratomycosis: optimization using D-optimal design and in vitro, ex vivo, and in vivo studies
This study aims to develop efficient topical therapy for keratomycosis using
sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to …
sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to …