Voltage-sensitive ion channels mediate action potentials in electrically excitable cells and
play important roles in signal transduction in other cell types. In the past several years, their …

Over the past two decades understanding the mechanisms of drug resistance has become a
central issue as its importance in medicine has assumed ever-increasing significance …

Overlapping complementary DNA clones were isolated from epithelial cell libraries with a
genomic DNA segment containing a portion of the putative cystic fibrosis (CF) locus, which is …

Previous studies have revealed the existence of a gene family that encodes a group of
neuronal nicotinic acetylcholine receptor (nAChR) subunits. Four members of this family …

Essential Medical Physiology, Third Edition, deals with the principal subjects covered in a
modern medical school physiology course. This thoroughly revised version includes …

The cellular localization of transcripts for a new putative agonist-binding subunit of the
neuronal nicotinic acetylcholine receptor (nAChR), α5, was examined using in situ …

Neuronal nicotinic acetylcholine receptors (nAChRs) have been a target for drug discovery
efforts, primarily for CNS indications, for the past two decades. While nicotine and related …

Loss of response after prolonged or repeated application of stimulus is generally termed
desensitization. A wide variety of phenomena occurring in living organisms falls under this …

Site-directed mutagenesis and expression in Xenopus oocytes were used to study
acetylcholine receptors in which serine residues (i) were replaced by alanines (α, δ …

The book describes in great detail the complex life cycle of fleas. The text is based on the
example of the cat flea (Ctenocephalides felis), the most important ectoparasite. The cat flea …