Long COVID or post-COVID-19 condition: past, present and future research directions

C Fernández-de-Las-Peñas, AV Raveendran… - Microorganisms, 2023 - mdpi.com
The presence of symptoms after an acute SARS-CoV-2 infection (long-COVID) has become
a worldwide healthcare emergency but remains underestimated and undertreated due to a …

Long COVID as a disease of accelerated biological aging: An opportunity to translate geroscience interventions

A Shafqat, MC Masters, U Tripathi, T Tchkonia… - Ageing Research …, 2024 - Elsevier
It has been four years since long COVID—the protracted consequences that survivors of
COVID-19 face—was first described. Yet, this entity continues to devastate the quality of life …

A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic …

K Peppercorn, CD Edgar, T Kleffmann, WP Tate - Scientific Reports, 2023 - nature.com
Of those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),~
10% develop the chronic post-viral debilitating condition, long COVID (LC). Although LC is a …

Risk factors for long COVID in older adults

Y Hu, Y Liu, H Zheng, L Liu - Biomedicines, 2023 - mdpi.com
As time has passed following the COVID-19 pandemic, individuals infected with SARS-CoV-
2 have gradually exhibited a variety of symptoms associated with long COVID in the …

High levels of IL-1β, TNF-α and MIP-1α one month after the onset of the acute SARS-CoV-2 infection, predictors of post COVID-19 in hospitalized patients

J Alonso-Domínguez, M Gallego-Rodríguez… - Microorganisms, 2023 - mdpi.com
The pandemic caused by SARS-CoV-2 infection has left behind a new symptomatology
called post COVID-19, or “long COVID”. The pathophysiological mechanisms still remain …

[HTML][HTML] Neurological Complications of COVID-19: Unraveling the Pathophysiological Underpinnings and Therapeutic Implications

A Vashisht, V Vashisht, H Singh, P Ahluwalia… - Viruses, 2024 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease (COVID-19), induced a global pandemic with a diverse array of clinical …

Reduced monocyte proportions and responsiveness in convalescent COVID-19 patients

EV Ravkov, ESCP Williams, M Elgort… - Frontiers in …, 2024 - frontiersin.org
Introduction The clinical manifestations of acute severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) …

Unique immune and inflammatory cytokine profiles may define long COVID syndrome

LT Allan-Blitz, O Akbari, N Kojima, E Saavedra… - Clinical and …, 2023 - Springer
Purpose Long COVID is estimated to occur in 5–10% of individuals after acute SARS-CoV-2
infection. However, the pathophysiology driving the disease process is poorly understood …

Proinflammatory cytokine profiles in both mild symptomatic and asymptomatic SARS-CoV-2-infected Egyptian individuals and a proposed relationship to post-COVID …

MM Bahgat, R Nadeem, MH Nasraa, K Amer… - Viral …, 2023 - liebertpub.com
Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection is associated
with proinflammatory cytokine release as mediators of host antiviral response to the …

Different polarization and functionality of CD4+ T helper subsets in people with post-COVID condition

C Sánchez-Menéndez, O de la Calle-Jiménez… - Frontiers in …, 2024 - frontiersin.org
Introduction After mild COVID-19 that does not require hospitalization, some individuals
develop persistent symptoms that may worsen over time, producing a multisystemic …