Steven M. Greenberg, MD, PhD, FAHA, Chair; Wendy C. Ziai, MD, MPH, FAHA, Vice Chair;
Charlotte Cordonnier, MD, PhD; Dar Dowlatshahi, MD, PhD, FAHA; Brandon Francis, MD …

Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

The global health burden of chronic kidney disease is rapidly rising, and chronic kidney
disease is an important risk factor for cerebrovascular disease. Proposed underlying …

'Covert'cerebral small vessel disease (ccSVD) is common on neuroimaging in persons
without overt neurological manifestations, and increases the risk of future stroke, cognitive …

The link between heart and brain continues to be a matter of great interest for the scientific
community. One of the most established associations between the two is that the heart is a …

Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

Purpose Many daily-life clinical decisions in patients with cerebrovascular disease and
cognitive impairment are complex. Evidence-based information sustaining these decisions …

Hypertension is the most important vascular risk factor for stroke; therefore, optimal blood
pressure (BP) management is essential for the prevention of recurrent stroke; lowering BP …

This comprehensive narrative review explores the concept of neuro-vulnerability in energy
metabolism regulation and its implications for metabolic disorders. The review highlights the …