The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
P Mehrbod, SR Ande, J Alizadeh, S Rahimizadeh… - Virulence, 2019 - Taylor & Francis
Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
[HTML][HTML] Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development
Q Wan, D Song, H Li, M He - Signal transduction and targeted therapy, 2020 - nature.com
Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …
Pathobiology of Japanese encephalitis virus infection
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …
[HTML][HTML] eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus
Y Li, W Jiang, Q Niu, Y Sun, C Meng, L Tan… - Cell death & …, 2019 - nature.com
Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively
kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the …
kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the …
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage
U Ashraf, Z Ding, S Deng, J Ye, S Cao, Z Chen - Virulence, 2021 - Taylor & Francis
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by
Japanese encephalitis virus. During the virus infection of the central nervous system …
Japanese encephalitis virus. During the virus infection of the central nervous system …
[HTML][HTML] The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
M Luhr, ML Torgersen, P Szalai, A Hashim… - Journal of Biological …, 2019 - ASBMB
Endoplasmic reticulum (ER) stress is thought to activate autophagy via unfolded protein
response (UPR)-mediated transcriptional up-regulation of autophagy machinery …
response (UPR)-mediated transcriptional up-regulation of autophagy machinery …
The endoplasmic reticulum unfolded protein response–homeostasis, cell death and evolution in virus infections
Viruses elicit cell and organismic stress, and offset homeostasis. They trigger intrinsic, innate
and adaptive immune responses, which limit infection. Viruses restore homeostasis by …
and adaptive immune responses, which limit infection. Viruses restore homeostasis by …
[HTML][HTML] Endoplasmic reticulum stress-associated neuronal death and innate immune response in neurological diseases
M Shi, Y Chai, J Zhang, X Chen - Frontiers in immunology, 2022 - frontiersin.org
Neuronal death and inflammatory response are two common pathological hallmarks of
acute central nervous system injury and chronic degenerative disorders, both of which are …
acute central nervous system injury and chronic degenerative disorders, both of which are …
[HTML][HTML] Mechanisms of neuroinvasion and neuropathogenesis by pathologic flaviviruses
L de Vries, AT Harding - Viruses, 2023 - mdpi.com
Flaviviruses are present on every continent and cause significant morbidity and mortality. In
many instances, severe cases of infection with flaviviruses involve the invasion of and …
many instances, severe cases of infection with flaviviruses involve the invasion of and …
Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways
P Sun, J Jin, L Wang, J Wang, H Zhou, Q Zhang… - Veterinary …, 2021 - Elsevier
Porcine epidemic diarrhea virus (PEDV), the causative agent of PED, belongs to the genus
Alphacoronavirus in the family Coronaviridae. Reactive oxygen species (ROS), endoplasmic …
Alphacoronavirus in the family Coronaviridae. Reactive oxygen species (ROS), endoplasmic …