Metal–organic frameworks for the removal of toxic industrial chemicals and chemical warfare agents

NS Bobbitt, ML Mendonca, AJ Howarth… - Chemical Society …, 2017 - pubs.rsc.org
Owing to the vast diversity of linkers, nodes, and topologies, metal–organic frameworks can
be tailored for specific tasks, such as chemical separations or catalysis. Accordingly, these …

Metal organic frameworks mimicking natural enzymes: a structural and functional analogy

I Nath, J Chakraborty, F Verpoort - Chemical Society Reviews, 2016 - pubs.rsc.org
In this review, we have portrayed the structure, synthesis and applications of a variety of
biomimetic MOFs from an unprecedented angle. Synthetic MOF analogues of five distinct …

Zirconium-based metal–organic frameworks for the catalytic hydrolysis of organophosphorus nerve agents

KO Kirlikovali, Z Chen, T Islamoglu… - … applied materials & …, 2020 - ACS Publications
Organophoshorus nerve agents are among the most toxic chemicals known to humans, and
because of their unfortunate recent use despite international bans, there is an urgent need …

Acetylcholinesterase inhibitors: pharmacology and toxicology

MB Colovic, DZ Krstic… - Current …, 2013 - ingentaconnect.com
Acetylcholinesterase is involved in the termination of impulse transmission by rapid
hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the …

Evaluating pesticide degradation in the environment: blind spots and emerging opportunities

K Fenner, S Canonica, LP Wackett, M Elsner - science, 2013 - science.org
The benefits of global pesticide use come at the cost of their widespread occurrence in the
environment. An array of abiotic and biotic transformations effectively removes pesticides …

Fibrous Zr‐MOF Nanozyme Aerogels with Macro‐Nanoporous Structure for Enhanced Catalytic Hydrolysis of Organophosphate Toxins

K Ma, YH Cheung, KO Kirlikovali, H Xie… - Advanced …, 2023 - Wiley Online Library
Metal–organic frameworks (MOFs) with Lewis acid catalytic sites, such as zirconium‐based
MOFs (Zr‐MOFs), comprise a growing class of phosphatase‐like nanozymes that can …

Instantaneous hydrolysis of nerve‐agent simulants with a six‐connected zirconium‐based metal–organic framework

SY Moon, Y Liu, JT Hupp, OK Farha - Angewandte Chemie, 2015 - Wiley Online Library
A nerve‐agent simulant based on a phosphate ester is hydrolyzed using a MOF‐based
catalyst. Suspensions of MOF‐808 (6‐connected), a material featuring 6‐connected …

Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics

PY Colin, B Kintses, F Gielen, CM Miton… - Nature …, 2015 - nature.com
Unculturable bacterial communities provide a rich source of biocatalysts, but their
experimental discovery by functional metagenomics is difficult, because the odds are …

Catalytic degradation of chemical warfare agents and their simulants by metal-organic frameworks

Y Liu, AJ Howarth, NA Vermeulen, SY Moon… - Coordination Chemistry …, 2017 - Elsevier
Since sulfur mustard was first used in World War I, significant efforts have been made in
materials and methods development for the adsorption and detoxification of different classes …

Quantum chemical studies of mechanisms for metalloenzymes

MRA Blomberg, T Borowski, F Himo, RZ Liao… - Chemical …, 2014 - ACS Publications
Two decades ago, theoretical model calculations played a truly minor role in understanding
mechanisms of redox-active metalloenzymes. The methods available to treat transition …