Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

Women face a disproportionate burden of stroke mortality and disability. Biologic sex and
sociocultural gender both contribute to differences in stroke risk factors, assessment …

Importance Stroke is the fifth leading cause of death and a leading cause of disability in the
United States, affecting nearly 800 000 individuals annually. Observations Sudden …

Importance Whether intravenous thrombolysis is needed in combination with mechanical
thrombectomy in patients with acute large vessel occlusion stroke is unclear. Objective To …

Objectives: Concise “synthetic” review of the state of the art of management of acute
ischemic stroke. Data Sources: Available literature on PubMed. Study Selection: We …

Importance Tirofiban is a highly selective nonpeptide antagonist of glycoprotein IIb/IIIa
receptor, which reversibly inhibits platelet aggregation. It remains uncertain whether …

Importance Whether recent changes in demographic characteristics and therapeutic
technologies have altered stroke outcomes remains unknown. Objective To determine …

Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

Importance For patients with large vessel occlusion strokes, it is unknown whether
endovascular treatment alone compared with intravenous thrombolysis plus endovascular …

Endovascular therapy (EVT) for acute ischemic stroke in selected patients has recently been
proven effective in several clinical trials, and the widespread adoption of thrombectomy into …