Inflammation is a process by which tissues respond to various insults. It is characterized by
upregulation of chemokines, cytokines, and pattern recognition receptors that sense …

Activins are dimeric glycoproteins belonging to the transforming growth factor beta
superfamily and resulting from the assembly of two beta subunits, which may also be …

Sotatercept is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein that improves
cardiopulmonary function in patients with pulmonary arterial hypertension (PAH) by …

Transforming growth factor β (TGFβ) superfamily members are closely associated with tissue
remodelling events and reproductive processes. This review summarises the current state of …

The TGF-β superfamily of cytokines plays pivotal roles in the regulation of immune
responses protecting against or contributing to diseases, such as, allergy, autoimmunity and …

Follicular helper T cells (TFH cells) are CD4+ T cells specialized in helping B cells and are
associated both with protective antibody responses and autoimmune diseases. The promise …

Activins are transforming growth factor β superfamily members, which were originally
identified as inducers of follicle-stimulating hormone release from the pituitary. In recent …

In recent years, a significant amount of research has examined the controversial role of
activin A in cancer. Activin A, a member of the transforming growth factor β (TGFβ) …

Activin A, a member of the TGF-β superfamily, is a pluripotent growth and differentiation
factor. In this study, we report that murine Th cells produce activin A upon activation. Activin …

Embryo implantation and trophoblast invasion are tightly regulated processes, involving
sophisticated communication between maternal decidual and fetal trophoblast cells …