Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

EB Hunziker - Osteoarthritis and cartilage, 2002 - Elsevier
Objective To review the basic scientific status of repair in articular cartilage tissue and to
assess the efficiency of current clinical therapies instigated for the treatment of structural …

Recent developments in ring opening polymerization of lactones for biomedical applications

AC Albertsson, IK Varma - Biomacromolecules, 2003 - ACS Publications
Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used
worldwide as bioresorbabale devices in surgery (orthopaedic devices, sutures, stents, tissue …

The role of bioreactors in tissue engineering

I Martin, D Wendt, M Heberer - TRENDS in Biotechnology, 2004 - cell.com
Ex vivo engineering of living tissues is a rapidly developing area with the potential to impact
significantly on a wide-range of biomedical applications. Major obstacles to the generation …

Tissue engineering for regeneration of articular cartilage

JS Temenoff, AG Mikos - Biomaterials, 2000 - Elsevier
Joint pain due to cartilage degeneration is a serious problem, affecting people of all ages.
Although many techniques, often surgical, are currently employed to treat this affliction, none …

Biodegradable polymeric scaffolds for musculoskeletal tissue engineering

CM Agrawal, RB Ray - … Research: An Official Journal of The …, 2001 - Wiley Online Library
Biodegradable scaffolds have played an important role in a number of tissue engineering
attempts over the past decade. The goal of this review article is to provide a brief overview of …

Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair

J Kisiday, M Jin, B Kurz, H Hung… - Proceedings of the …, 2002 - National Acad Sciences
Emerging medical technologies for effective and lasting repair of articular cartilage include
delivery of cells or cell-seeded scaffolds to a defect site to initiate de novo tissue …

Engineering cartilage tissue

C Chung, JA Burdick - Advanced drug delivery reviews, 2008 - Elsevier
Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …

The role of tissue engineering in articular cartilage repair and regeneration

L Zhang, J Hu, KA Athanasiou - Critical Reviews™ in …, 2009 - dl.begellhouse.com
Articular cartilage repair and regeneration continue to be largely intractable because of the
poor regenerative properties of this tissue. The field of articular cartilage tissue engineering …

Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels

RL Mauck, MA Soltz, CCB Wang… - J. Biomech …, 2000 - asmedigitalcollection.asme.org
Due to its avascular nature, articular cartilage exhibits a very limited capacity to regenerate
and to repair. Although much of the tissue-engineered cartilage in existence has been …

A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage

FT Moutos, LE Freed, F Guilak - Nature materials, 2007 - nature.com
Tissue engineering seeks to repair or regenerate tissues through combinations of implanted
cells, biomaterial scaffolds and biologically active molecules. The rapid restoration of tissue …