[HTML][HTML] Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms

A Alizadeh, SM Dyck, S Karimi-Abdolrezaee - Frontiers in neurology, 2019 - frontiersin.org
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

[HTML][HTML] Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

[PDF][PDF] Targeting aquaporin-4 subcellular localization to treat central nervous system edema

P Kitchen, MM Salman, AM Halsey, C Clarke-Bland… - Cell, 2020 - cell.com
Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All
potential pharmacological interventions have failed in clinical trials, meaning that symptom …

[HTML][HTML] Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy

F Cofano, M Boido, M Monticelli, F Zenga… - International journal of …, 2019 - mdpi.com
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …

[HTML][HTML] Traumatic spinal cord injury

CS Ahuja, JR Wilson, S Nori, M Kotter… - Nature reviews Disease …, 2017 - nature.com
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …

[HTML][HTML] Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury

C Li, Z Wu, L Zhou, J Shao, X Hu, W Xu… - Signal transduction and …, 2022 - nature.com
Spinal cord injury (SCI) involves diverse injury responses in different cell types in a
temporally and spatially specific manner. Here, using single-cell transcriptomic analyses …

Acute traumatic spinal cord injury

I Eli, DP Lerner, Z Ghogawala - Neurologic Clinics, 2021 - neurologic.theclinics.com
Acute traumatic spinal cord injury (SCI) is typically associated with devastating outcomes.
The injury to the spinal cord results in damage to motor, sensory, and autonomic functions of …

Microenvironment imbalance of spinal cord injury

B Fan, Z Wei, X Yao, G Shi, X Cheng… - Cell …, 2018 - journals.sagepub.com
Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient
physiology and psychology. The microenvironment of the injured spinal cord is complicated …

Programmed cell death in spinal cord injury pathogenesis and therapy

Z Shi, S Yuan, L Shi, J Li, G Ning, X Kong… - Cell …, 2021 - Wiley Online Library
Spinal cord injury (SCI) always leads to functional deterioration due to a series of processes
including cell death. In recent years, programmed cell death (PCD) is considered to be a …

SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data

B De Leener, S Lévy, SM Dupont, VS Fonov, N Stikov… - Neuroimage, 2017 - Elsevier
For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …