Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host
immunity that damages tooth-supporting tissues, including the gingiva, periodontal ligament …

Dental caries, periodontal disease, and endodontic disease are major public health
concerns worldwide due to their impact on individuals' quality of life. The present problem of …

Pluronic F127 (PF127) hydrogel has been highlighted as a promising biomaterial for bone
regeneration, but the specific molecular mechanism remains largely unknown. Herein, we …

Surgical site infection (SSI) remains a significant risk for any clean orthopedic surgical
procedure. Complications resulting from an SSI often require a second surgery and lengthen …

Periodontal disease is a localized inflammatory disorder, with tissue destruction resulting
from the host response to bacterial antigens and irritants. Several other risk factors, such as …

Clotrimazole (CTZ) is a Biopharmaceutics Classification System (BCS) Class II drug having
a limited therapeutic potential because of its poor aqueous solubility and relatively short half …

The results of recent published studies focusing on the effect of azithromycin as an adjunct
to scaling and root planing (SRP) in the treatment of chronic periodontitis are inconsistent …

Biodegradable spray-dried chitosan microparticles loaded with clindamycin phosphate
(CDP) were formulated to deliver drugs locally into the periodontal pocket. The effects of …

Several chemical compounds are considered to be promising as adjuvants in the treatment
of periodontitis. Antimicrobials, anti-inflammatory drugs or, more recently, pro-regenerative …

Periodontitis is an inflammatory disease of gums involving degeneration of periodontal
ligaments, creation of periodontal pocket and resorption of alveolar bone, thus disrupting the …