Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

In the early 1920s, Warburg published experimental data on the enhanced conversion of
glucose to pyruvate (followed by lactate formation) even in the presence of abundant oxygen …

Metabolic reprogramming is a hallmark of cancer. Here, we demonstrate that tumour-
associated macrophages (TAMs) enhance the aerobic glycolysis and apoptotic resistance of …

The main features that are commonly attributed to mitochondria consist of the regulation of
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …

The roots and rhizomes of Rhodiola rosea L.(Crassulaceae), which is widely growing in
Northern Europe, North America, and Siberia, have been used since ancient times to …

Metabolic reprogramming is one of the main characteristics of malignant tumors. The
metabolic reprogramming of tumors is not only related to the characteristics of cancer cells …

Gliomas are a highly heterogeneous tumor, refractory to treatment and the most frequently
diagnosed primary brain tumor. Although the current WHO grading system (2016) …

Cancer metabolism is an essential aspect of tumorigenesis, as cancer cells have increased
energy requirements in comparison to normal cells. Thus, an enhanced metabolism is …

Pin1 is the only known peptidyl-prolyl cis–trans isomerase (PPIase) that specifically
recognizes and isomerizes the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) …

Cancer is one of the most serious public health issues worldwide, demanding ongoing
efforts to find novel therapeutic agents and approaches. Amid growing interest in the …