Selective immunoglobulin A deficiency (SI g AD) is the most common primary antibody
deficiency. Although more patients with SI g AD are asymptomatic, selected patients suffer …

To date, several germline mutations have been identified in the LRBA gene in patients
suffering from a variety of clinical symptoms. These mutations abolish the expression of the …

Abstract Selective IgA deficiency (SIgAD) is the most common primary immunodeficiency but
does not always result in clinical disease. This may in part be due to the definition based on …

Common variable immunodeficiency (CVID) is the most common clinical primary
immunodeficiency. It is characterized by a defect in B-cell differentiation to plasma and …

Selective IgA deficiency (SIgAD), characterized by a serum IgA level below 0.07 mg/ml,
while displaying normal serum levels of IgM and IgG antibodies, is the most frequently …

Selective IgA deficiency (sIgAD) is the most common primary immunodeficiency disease
(PID), with an estimated occurrence from about 1: 3000 to even 1: 150, depending on …

Selective immunoglobulin A deficiency (SIgAD) is the most common predominantly antibody
deficiency, with a wide range of presentations from asymptomatic to severe manifestations …

Common variable immunodeficiency (CVID) and selective IgA deficiency (SIgAD) are the
most common primary immunodeficiencies in human. Both diseases share clinical …

Introduction: For twenty years, two paradigms have been considered as the main genetic
contributors to immunoglobulin A deficiency, including cytogenetic defects involving large …

Background Primary antibody deficiency (PAD) is the most common group of primary
immunodeficiency disorders (PID), with a broad spectrum of clinical features ranging from …