American Society of Hematology 2019 guidelines for immune thrombocytopenia

C Neunert, DR Terrell, DM Arnold, G Buchanan… - Blood …, 2019 - ashpublications.org
Background: Despite an increase in the number of therapies available to treat patients with
immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist …

Updated international consensus report on the investigation and management of primary immune thrombocytopenia

D Provan, DM Arnold, JB Bussel, BH Chong… - Blood …, 2019 - ashpublications.org
Over the last decade, there have been numerous developments and changes in treatment
practices for the management of patients with immune thrombocytopenia (ITP). This article is …

[HTML][HTML] Thrombopoietin receptor agonists: ten years later

W Ghanima, N Cooper, F Rodeghiero, B Godeau… - …, 2019 - ncbi.nlm.nih.gov
The two thrombopoietin receptor agonists (TPO-RA), eltrombopag and romiplostim, were
licensed in the US for treatment of immune thrombocytopenia (ITP) in 2008 and, since then …

[HTML][HTML] Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review

C Neunert, N Noroozi, G Norman, GR Buchanan… - Journal of Thrombosis …, 2015 - Elsevier
Background The burden of severe bleeding in adults and children with immune
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and …

A review of romiplostim mechanism of action and clinical applicability

JB Bussel, G Soff, A Balduzzi, N Cooper… - Drug design …, 2021 - Taylor & Francis
Thrombocytopenia results from a variety of conditions, including radiation, chemotherapy,
autoimmune disease, bone marrow disorders, pathologic conditions associated with …

Management of adult patients with immune thrombocytopenia (ITP): a review on current guidance and experience from clinical practice

F Song, H Al-Samkari - Journal of Blood Medicine, 2021 - Taylor & Francis
Immune thrombocytopenia (ITP) is an autoimmune process resulting in increased
destruction and inadequate production of platelets that can result in bleeding, fatigue, and …

Thrombosis in immune thrombocytopenia—current status and future perspectives

D Swan, A Newland, F Rodeghiero… - British journal of …, 2021 - Wiley Online Library
Immune thrombocytopenia (ITP) is an autoimmune disorder in which a combination of
defective platelet production and enhanced clearance leads to thrombocytopenia. The …

Optimal use of thrombopoietin receptor agonists in immune thrombocytopenia

H Al-Samkari, DJ Kuter - Therapeutic advances in …, 2019 - journals.sagepub.com
The thrombopoietin receptor agonists (TPO-RAs) are a class of platelet growth factors
commonly used to treat immune thrombocytopenia (ITP). There are three agents that have …

[HTML][HTML] Immune thrombocytopenia in adults: modern approaches to diagnosis and treatment

H Al-Samkari, DJ Kuter - Seminars in thrombosis and …, 2020 - thieme-connect.com
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder affecting
approximately 1 in 20,000 people. Patients typically present with clinically benign …

[HTML][HTML] Current management of primary immune thrombocytopenia

D Provan, AC Newland - Advances in therapy, 2015 - Springer
Primary immune thrombocytopenia is an autoimmune disorder of unknown cause affecting
both children and adults. The low peripheral blood platelet count is caused by premature …