Fundamentals of intervertebral disc degeneration

S Kirnaz, C Capadona, T Wong, JL Goldberg… - World neurosurgery, 2022 - Elsevier
Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

[HTML][HTML] Global, regional and national burden of low back pain 1990–2019: a systematic analysis of the Global Burden of Disease study 2019

S Chen, M Chen, X Wu, S Lin, C Tao, H Cao… - Journal of orthopaedic …, 2022 - Elsevier
Background To comprehensively analyze the global level and trends of prevalence,
incidence and years lived with disability (YLDs) for low back pain (LBP) from 1990 to 2019 …

[HTML][HTML] Therapeutic approaches for peripheral and central neuropathic pain

D Szok, J Tajti, A Nyári, L Vécsei - Behavioural neurology, 2019 - hindawi.com
Neuropathic pain is a chronic secondary pain condition, which is a consequence of
peripheral or central nervous (somatosensory) system lesions or diseases. It is a devastating …

[HTML][HTML] Efficacy of core stability in non-specific chronic low back pain

A Frizziero, G Pellizzon, F Vittadini, D Bigliardi… - Journal of functional …, 2021 - mdpi.com
(1) Background: Management of chronic low back pain (cLBP) is often multidisciplinary,
involving a combination of treatments, including therapeutic exercises. Core stability …

Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain

C Gevers‐Montoro, B Provencher… - … Journal of Pain, 2021 - Wiley Online Library
Together, neck pain and back pain are the first cause of disability worldwide, accounting for
more than 10% of the total years lived with disability. In this context, chiropractic care …

Neuroimmune signatures in chronic low back pain subtypes

Z Alshelh, L Brusaferri, A Saha, E Morrissey, P Knight… - Brain, 2022 - academic.oup.com
We recently showed that patients with different chronic pain conditions (such as chronic low
back pain, fibromyalgia, migraine and Gulf War illness) demonstrated elevated brain and/or …

Neurotechnology for Pain

LE Fisher, SF Lempka - Annual Review of Biomedical …, 2023 - annualreviews.org
Neurotechnologies for treating pain rely on electrical stimulation of the central or peripheral
nervous system to disrupt or block pain signaling and have been commercialized to treat a …

[HTML][HTML] An update of current therapeutic approach for Intervertebral Disc Degeneration: A review article

F Mahyudin, CRS Prakoeswa, HB Notobroto… - Annals of Medicine and …, 2022 - Elsevier
Intervertebral disc degeneration is a natural process of aging. It can cause physical,
psychological, and socioeconomic impact due to the decreasing function of the spine and …

[HTML][HTML] The mediation effect of pain on the relationship between Kinesiophobia and lumbar joint position sense in chronic low Back pain individuals: A cross-sectional …

MA ALMohiza, RS Reddy, F Asiri, A Alshahrani… - International Journal of …, 2023 - mdpi.com
(1) Background: Fear of movement (kinesiophobia) and impaired lumbar joint position sense
(LJPS) play a vital role in developing and maintaining non-specific chronic low back pain …

[HTML][HTML] Depression and pain: use of antidepressants

H Bonilla-Jaime, JA Sánchez-Salcedo… - Current …, 2022 - ncbi.nlm.nih.gov
Background: Emotional disorders are common comorbid affectations that exacerbate the
severity and persistence of chronic pain. Specifically, depressive symptoms can lead to an …