Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

The use of psychoactive drugs is a wide spread behaviour in human societies. The
systematic use of a drug requires the establishment of different drug use-associated …

The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) is
a popular recreational drug among young people, particularly those involved in the dance …

Serotonin1A-receptors (5-HT1A-Rs) are important components of the 5-HT system in the
brain. As somatodendritic autoreceptors they control the activity of 5-HT neurons, and, as …

BACKGROUND AND PURPOSE Here, we have compared the neurochemical profile of
three new cathinones, butylone, mephedrone and methylone, in terms of their potential to …

Abstract In preclinical studies, 3, 4‐methylenedioxymethamphetamine (MDMA,'Ecstasy') has
been shown to release serotonin (5‐HT), dopamine and norepinephrine. However, the role …

Serotonin is a monoamine neurotransmitter, which is phylogenetically conserved in a wide
range of species from nematodes to humans. In mammals, age-related changes in serotonin …

Methylenedioxymethamphetamine (MDMA, Ecstasy) is a very popular drug of abuse. This
has led to new intense concerns relevant to its nefarious neuropsychiatric effects. These …

Adolescence is a period of profound developmental changes, which run the gamut from
behavioral and neural to physiological and hormonal. It is also a time at which there is an …

Bipolar disorder (BD) has been a particularly challenging illness for the development of
adequate animal models for neurobiological studies. These difficulties are largely related to …