[HTML][HTML] Analysis of DFS70 pattern and impact on ANA screening using a novel HEp-2 ELITE/DFS70 knockout substrate

K Malyavantham, L Suresh - Autoimmunity Highlights, 2017 - Springer
Indirect immunofluorescence (IIF) using human epithelial cell (HEp-2) substrate is a widely
used and the recommended method for screening of antinuclear antibodies (ANA). Dense …

[PDF][PDF] Prevalence of anti-DFS70 antibodies in patients with and without systemic autoimmune rheumatic diseases

O Shovman, B Gilburd, C Chayat, H Amital… - Clin Exp …, 2018 - clinexprheumatol.org
Objective Autoantibodies to the dense fine speckled 70 (DFS70) antigen are common
among antinuclear antibodies (ANA) positive healthy individuals (HI). We assessed the …

[HTML][HTML] Recognition and relevance of anti-DFS70 autoantibodies in routine antinuclear autoantibodies testing at a community hospital

JB Carter, S Carter, S Saschenbrecker… - Frontiers in …, 2018 - frontiersin.org
Antinuclear autoantibodies (ANA) displaying a dense fine speckled pattern (DFS, ICAP AC-
2) on HEp-2 cells are frequently observed in clinical laboratory referrals, often associated …

[HTML][HTML] Prevalence and serological profile of anti-DFS70 positive subjects from a routine ANA cohort

T Carbone, V Pafundi, G Tramontano, M Gilio… - Scientific Reports, 2019 - nature.com
Abstract Anti-Dense Fine Speckled 70 (DFS70) antibodies are a common finding in clinical
laboratory referrals. High prevalence of DFS70 autoantibodies in healthy population and …

[HTML][HTML] Anti-DFS70 antibodies among patient and healthy population cohorts in China: results from a multicenter training program showing spontaneous abortion and …

B Zheng, Z Wang, RA Mora, A Liu, C Li, D Liu… - Frontiers in …, 2020 - frontiersin.org
Objective Anti-DFS70 antibodies correlating with the nuclear dense fine speckled (DFS)
pattern in the HEp-2 indirect immunofluorescence assay (IFA) are less common in patients …

[HTML][HTML] Low prevalence of anti-DFS70 antibodies in children with ANA-associated autoimmune disease

M Freudenhammer, U Salzer, A Heselich… - Frontiers in …, 2022 - frontiersin.org
Introduction Anti-DFS70 antibodies occur in healthy individuals with various medical
conditions. Unlike other anti-nuclear autoantibodies (ANA), they are not associated with …

Infusion of anti-DFS70 antibodies prolonged survival of lupus-prone mice

G Aljadeff, A Shemer, I Katz, LEC Andrade… - Lupus, 2021 - journals.sagepub.com
Background Systemic-lupus-nephritis is a chronic autoimmune disease characterized by
immune complex deposition and a flare of autoantibodies and leading to renal injury …

[HTML][HTML] Potential value of autoantibodies as biomarkers of chronic graft-versus-host disease after allogeneic stem cell transplantation

B Hao, S Gao, Y Sang, L Wang, X Meng… - Journal of Zhejiang …, 2019 - ncbi.nlm.nih.gov
We investigated the value of autoantibodies as biomarkers of chronic graft-versus-host
disease (cGVHD) by analyzing the autoantibody profiles of 65 patients (34 cGVHD and 31 …

Simultaneous distinction of monospecific and mixed DFS70 patterns during ANA screening with a novel HEp-2 ELITE/DFS70 knockout substrate

KS Malyavantham, L Suresh - JoVE (Journal of Visualized Experiments), 2018 - jove.com
Systemic autoimmune connective tissue disorders are characterized by circulating
antinuclear antibodies (ANA). Although there are several technologies available for ANA …

Anti-DFS70 autoantibodies in HIV-1-positive individuals

D Pérez, D Azoulay - Current Opinion in Rheumatology, 2018 - journals.lww.com
The anti-DFS70 antibodies bind to the DFS70 autoantigen in the same region as the HIV-IN.
This fact makes the autoantibodies a potential treatment for HIV-1-infected individuals. Blood …