The epidemiology of benzodiazepine misuse: a systematic review

VR Votaw, R Geyer, MM Rieselbach… - Drug and alcohol …, 2019 - Elsevier
Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

Prevalence of childhood maltreatment among people with opioid use disorder: A systematic review and meta-analysis

T Santo Jr, G Campbell, N Gisev, LT Tran… - Drug and alcohol …, 2021 - Elsevier
Background Experience of childhood maltreatment (CM) is a risk factor for opioid use
disorder (OUD). CM is also associated with comorbid mental disorders and poor treatment …

Association of opioid agonist treatment with all-cause mortality and specific causes of death among people with opioid dependence: a systematic review and meta …

T Santo, B Clark, M Hickman, J Grebely… - JAMA …, 2021 - jamanetwork.com
Importance Mortality among people with opioid dependence is higher than that of the
general population. Opioid agonist treatment (OAT) is an effective treatment for opioid …

The impact of childhood abuse on inpatient substance users: Specific links with risky sex, aggression, and emotion dysregulation

AN Banducci, EM Hoffman, CW Lejuez… - Child abuse & neglect, 2014 - Elsevier
Adults with substance use disorders (SUDs) report a high prevalence of childhood abuse.
Research in the general population suggests specific types of abuse lead to particular …

Sex differences in cocaine/heroin users: drug-use triggers and craving in daily life

AP Kennedy, DH Epstein, KA Phillips… - Drug and alcohol …, 2013 - Elsevier
Background Studies of sex differences have shown that men and women with drug-use
disorders differ in course and outcome and in cue-induced activation of putative brain …

Neurodevelopmental origins of substance use disorders: Evidence from animal models of early‐life adversity and addiction

SC Levis, TZ Baram, SV Mahler - European Journal of …, 2022 - Wiley Online Library
Addiction is a chronic relapsing disorder with devastating personal, societal, and economic
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …

Evidence of CNIH3 involvement in opioid dependence

EC Nelson, A Agrawal, AC Heath, R Bogdan… - Molecular …, 2016 - nature.com
Opioid dependence, a severe addictive disorder and major societal problem, has been
demonstrated to be moderately heritable. We conducted a genome-wide association study …

The Collaborative Study on the Genetics of Alcoholism: Overview

A Agrawal, SJ Brislin, KK Bucholz… - Genes, Brain and …, 2023 - Wiley Online Library
Alcohol use disorders (AUD) are commonly occurring, heritable and polygenic disorders
with etiological origins in the brain and the environment. To outline the causes and …

Sex differences in prevalence and comorbidity of alcohol and drug use disorders: results from wave 2 of the National Epidemiologic Survey on Alcohol and Related …

RB Goldstein, DA Dawson, SP Chou… - Journal of studies on …, 2012 - jsad.com
Objective: The present study examined sex differences in lifetime Axis I and II psychiatric
comorbidity of DSM-IV alcohol use disorders (AUDs) and drug use disorders (DUDs) among …

Causes of death in a cohort treated for opioid dependence between 1985 and 2005

L Degenhardt, S Larney, D Randall, L Burns, W Hall - Addiction, 2014 - Wiley Online Library
Aims To examine changes in causes of death in a cohort treated for opioid dependence,
across time and age; quantify years of potential life lost (YPLL); and identify avoidable …