Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Risk factors for endometrial cancer: an umbrella review of the literature

O Raglan, I Kalliala, G Markozannes… - … journal of cancer, 2019 - Wiley Online Library
Although many risk factors could have causal association with endometrial cancer, they are
also prone to residual confounding or other biases which could lead to over‐or …

Lenvatinib plus pembrolizumab for advanced endometrial cancer

V Makker, N Colombo, A Casado Herráez… - … England Journal of …, 2022 - Mass Medical Soc
Background Standard therapy for advanced endometrial cancer after failure of platinum-
based chemotherapy remains unclear. Methods In this phase 3 trial, we randomly assigned …

[PDF][PDF] Cancer statistics, 2022.

RL Siegel, KD Miller, HE Fuchs… - CA: a cancer journal for …, 2022 - medicine-opera.com
Each year, the American Cancer Society estimates the numbers of new cancer cases and
deaths in the United States and compiles the most recent data on population-based cancer …

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

H Sung, J Ferlay, RL Siegel… - CA: a cancer journal …, 2021 - Wiley Online Library
This article provides an update on the global cancer burden using the GLOBOCAN 2020
estimates of cancer incidence and mortality produced by the International Agency for …

Randomized phase II trial of carboplatin–paclitaxel compared with carboplatin–paclitaxel–trastuzumab in advanced (stage III–IV) or recurrent uterine serous …

AN Fader, DM Roque, E Siegel, N Buza, P Hui… - Clinical Cancer …, 2020 - AACR
Abstract Purpose: Uterine-serous-carcinoma (USC) is an aggressive variant of endometrial
cancer. On the basis of preliminary results of a multicenter, randomized phase II trial …

Clinical actionability of molecular targets in endometrial cancer

ME Urick, DW Bell - Nature Reviews Cancer, 2019 - nature.com
Abstract Endometrial cancer accounts for~ 76,000 deaths among women each year
worldwide. Disease mortality and the increasing number of new diagnoses make …

Variations in incidence and mortality rates of endometrial cancer at the global, regional, and national levels, 1990–2019

B Gu, X Shang, M Yan, X Li, W Wang, Q Wang… - Gynecologic …, 2021 - Elsevier
Background Endometrial cancer (EC) is a commonly diagnosed cancer in women. A
comprehensive knowledge of its epidemiological features is essential for understanding the …

Evaluating intrinsic and non-intrinsic cancer risk factors

S Wu, W Zhu, P Thompson, YA Hannun - Nature communications, 2018 - nature.com
Discriminating the contribution of unmodifiable random intrinsic DNA replication errors ('bad
luck') to cancer development from those of other factors is critical for understanding cancer in …

Cancer statistics, 2018

RL Siegel, KD Miller, A Jemal - CA: a cancer journal for …, 2018 - Wiley Online Library
Abstract Each year, the American Cancer Society estimates the numbers of new cancer
cases and deaths that will occur in the United States and compiles the most recent data on …