Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Extracorporeal blood purification is proposed as an adjuvant therapy for sepsis, aiming at
controlling the associated dysregulation of the immune system, which is known to induce …

Background Septic shock, a leading cause of acute kidney injury, induces release of pro-
/anti-inflammatory mediators, leading to increased mortality and poor renal recovery. This is …

Severe acute kidney injury (AKI), especially when caused or accompanied by sepsis, is
associated with prolonged hospitalization, progression to chronic kidney disease (CKD) …

Sepsis is one of the leading causes of morbidity and mortality worldwide. It is characterized
by a dysregulated immune response to infections that results in life-threatening organ …

Cytokines play a critical role in coordinating and amplifying a host immune response to
infection. The normal pattern of localized and systemic release of proinflammatory and anti …

Background The oXiris is a novel filter for continuous renal replacement therapy (CRRT)
featuring an adsorption coating to adsorb endotoxins and remove inflammatory mediators …

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection; it carries a risk for mortality, considerably exceeding that of a mere …

Critically ill patients with sepsis and severe COVID-19 are commonly characterized by a
dysregulated immune response and an acute kidney injury. Continuous renal replacement …

Background: Sepsis is a dysregulated host response to an infection and can result in organ
dysfunctions and death. Extracorporeal blood purification techniques aim to improve the …