Precision medicine and radiogenomics in breast cancer: new approaches toward diagnosis and treatment

K Pinker, J Chin, AN Melsaether, EA Morris, L Moy - Radiology, 2018 - pubs.rsna.org
Precision medicine is medicine optimized to the genotypic and phenotypic characteristics of
an individual and, when present, his or her disease. It has a host of targets, including genes …

[HTML][HTML] Insights into the New Molecular Updates in Acute Myeloid Leukemia Pathogenesis

D Demir - Genes, 2023 - mdpi.com
As our understanding of the biologic basis of acute myeloid leukemia evolves, so do the
classification systems used to describe this group of cancers. Early classification systems …

[HTML][HTML] OncoKids: a comprehensive next-generation sequencing panel for pediatric malignancies

MC Hiemenz, DG Ostrow, TM Busse, J Buckley… - The Journal of Molecular …, 2018 - Elsevier
The OncoKids panel is an amplification-based next-generation sequencing assay designed
to detect diagnostic, prognostic, and therapeutic markers across the spectrum of pediatric …

[HTML][HTML] Cell-free HPV-DNA as a biomarker for oropharyngeal squamous cell carcinoma—a step towards personalized medicine?

N Wuerdemann, R Jain, A Adams, EJM Speel… - Cancers, 2020 - mdpi.com
Simple Summary Human papillomavirus (HPV)-related oropharyngeal squamous cell
carcinoma (OPSCC) is a distinct tumor entity with relatively favorable overall survival …

[HTML][HTML] Precision oncology in Latin America: Current situation, challenges and perspectives

A Calderón-Aparicio, A Orue - ecancermedicalscience, 2019 - ncbi.nlm.nih.gov
Background Anti-cancer cytotoxic treatments like platinum-derived compounds often show
low therapeutic efficacy, high-risk side effects and resistance. Hence, targeted treatments …

Prognostic role of microRNA-155 in patients with leukemia: A meta-analysis

X Zhang, Y Wang, Q Guo, Y Diao, H Liu, G Song… - Clinica Chimica …, 2018 - Elsevier
Background Recent studies have shown that microRNA-155 (miR-155) is correlated with
clinical outcomes of leukemia. This meta-analysis explores to evaluate the prognostic value …

Upregulation of O‐GlcNAc transferase is involved in the pathogenesis of acute myeloid leukemia

N He, D Ma, Y Tan, M Liu - Asia‐Pacific Journal of Clinical …, 2022 - Wiley Online Library
Background Acute myeloid leukemia (AML) is the most common acute leukemia in adults.
Patients have a low survival rate and a high recurrence rate, and AML is a highly …

miR-149-3p suppressed epithelial–mesenchymal transition and tumor development in acute myeloid leukemia

Y Tian, Y Jiang, X Dong, Y Chang, J Chi, X Chen - Hematology, 2021 - Taylor & Francis
Objective Acute myeloid leukemia (AML) is a form of primary acute leukemia with high
mortality. Our previous study demonstrated that miR-149-3p was down-regulated in …

Gene mutation patterns of Chinese acute myeloid leukemia patients by targeted next-generation sequencing and bioinformatic analysis

X Han, W Li, N He, P Feng, Y Pang, C Ji, D Ma - Clinica Chimica Acta, 2018 - Elsevier
Purposes The conventional risk stratification of acute myeloid leukemia (AML), based on
cytogenetics, cannot meet the demand for accurate prognostic evaluations. In recent years …

[HTML][HTML] Радиогеномика рака молочной железы-новый вектор междисциплинарной интеграции лучевых и молекулярнобиологических технологий (обзор …

НИ Рожкова, ВК Боженко, ИИ Бурдина… - Медицинский …, 2020 - med-alphabet.com
Аннотация В обзоре представлены последние данные о развитии нового направления
междисциплинарной интеграции цифровых лучевых и молекулярно-биологических …