Organoboron reagents represent a unique class of compounds because of their utility in
modern synthetic organic chemistry, often affording unprecedented reactivity. The …

Chiral organoboronates have played a critical role in organic chemistry and in the
development of materials science and pharmaceuticals. Much effort has been devoted to …

Organoboronates represent a cornerstone functional group in modern synthesis owing to
their unique reactivity and divergent synthetic capability. Copper catalysis has become one …

Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

Catalytic asymmetric C–C bond formation with alkylcopper intermediates as carbon
nucleophiles is now textbook chemistry. Related chemistry with boron and silicon …

Catalytic enantioselective functionalization of cyclobutenes constitutes a general and
modular strategy for construction of enantioenriched complex cyclobutanes bearing multiple …

We report a nickel-catalyzed cross-electrophile coupling reaction of aryl chlorides and
heteroaryl chlorides enabled by a synergistic combination consisting of halide effects and …

Cyclobutyl moieties in drug molecules are rare, and in general, they are minimally
substituted and stereochemically simple. Methods to assemble structurally complex …

Quinazolinones are common substructures in molecules of medicinal importance. We report
an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged …

Herein, we demonstrate the use of E/Z mixtures of α, α-disubstituted crotylhydrazones to
obtain spirocyclic vinylcyclobutanes in a diastereoselective fashion. We show 24 examples …