Vascular mechanotransduction

MJ Davis, S Earley, YS Li, S Chien - Physiological reviews, 2023 - journals.physiology.org
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

[HTML][HTML] Spatiotemporal modulation of nitric oxide and Notch signaling by hemodynamic-responsive Trpv4 is essential for ventricle regeneration

C Yu, X Li, J Ma, S Liang, Y Zhao, Q Li… - Cellular and Molecular …, 2024 - Springer
Zebrafish have a remarkable ability to regenerate injured hearts. Altered hemodynamic
forces after larval ventricle ablation activate the endocardial Klf2a-Notch signaling cascade …

Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos

AG Cairelli, A Gendernalik, WX Chan… - The Journal of …, 2024 - Wiley Online Library
Cardiac trabeculae are uneven ventricular muscular structures that develop during early
embryonic heart development at the outer curvature of the ventricle. Their biomechanical …