The Respiratory Mechanics of COVID-19 Acute Respiratory Distress Syndrome—Lessons Learned?

RL Kummer, JJ Marini - Journal of Clinical Medicine, 2024 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a well-defined clinical entity characterized by
the acute onset of diffuse pulmonary injury and hypoxemia not explained by fluid overload …

Optimized ventilation power to avoid VILI

LT Thornton, JJ Marini - Journal of Intensive Care, 2023 - Springer
The effort to minimize VILI risk must be multi-pronged. The need to adequately ventilate, a
key determinant of hazardous power, is reduced by judicious permissive hypercapnia …

Physical manoeuvres in patients with ARDS and low compliance: bedside approaches to detect lung hyperinflation and optimise mechanical ventilation

E Rezoagli, L Bastia, L Brochard… - European Respiratory …, 2023 - Eur Respiratory Soc
Mechanical ventilation in acute respiratory distress syndrome (ARDS) aims at delivering
protective tidal volume within lungs that are characterised both by collapsed and …

Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP

J Selickman, P Tawfik, PS Crooke, DJ Dries, J Shelver… - Critical Care, 2022 - Springer
Background Chest wall loading has been shown to paradoxically improve respiratory
system compliance (CRS) in patients with moderate to severe acute respiratory distress …

Paradoxical positioning: does “head up” always improve mechanics and lung protection?

J Selickman, PS Crooke, P Tawfik, DJ Dries… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: Head-elevated body positioning, a default clinical practice, predictably
increases end-expiratory transpulmonary pressure and aerated lung volume. In acute …

Two-lung ventilation in video-assisted thoracoscopic esophagectomy in prone position: a systematic review

MA Daghmouri, MA Chaouch, F Depret… - … Critical Care & Pain …, 2022 - Elsevier
Esophageal cancer surgery is still carrying a high risk of morbidity and mortality. That is why
some anesthesia strategies have tried to reduce those postoperative complications. In this …

Chest wall loading during supine and prone position in patients with COVID-19 ARDS: effects on respiratory mechanics and gas exchange

M Umbrello, S Lassola, A Sanna, R Pace, S Magnoni… - Critical Care, 2022 - Springer
Background Recent reports of patients with severe, late-stage COVID-19 ARDS with
reduced respiratory system compliance described paradoxical decreases in plateau …

Prone Positioning Decreases Inhomogeneity and Improves Dorsal Compliance in Invasively Ventilated Spontaneously Breathing COVID-19 Patients—A Study Using …

C Pierrakos, FLIM van der Ven, MR Smit, LA Hagens… - Diagnostics, 2022 - mdpi.com
Background: We studied prone positioning effects on lung aeration in spontaneously
breathing invasively ventilated patients with coronavirus disease 2019 (COVID-19) …

Chest wall loading in the ICU: pushes, weights, and positions

J Selickman, JJ Marini - Annals of Intensive Care, 2022 - Springer
Clinicians monitor mechanical ventilatory support using airway pressures—primarily the
plateau and driving pressure, which are considered by many to determine the safety of the …

胸壁压迫在急性呼吸窘迫综合征通气中的应用前景

柳宇华, 张钊培, 刘晓青, 刘学松 - 广西医科大学学报, 2024 - journal.gxmu.edu.cn
急性呼吸窘迫综合征(ARDS) 是一种危及生命的非心源性肺水肿. 尽管肺保护性通气策略是
ARDS 治疗的基石, 但部分患者仍无法有效缓解低氧血症或减少呼吸机相关性肺损伤 …