Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

The FERM domain protein Merlin, encoded by the NF2 tumor suppressor gene, regulates
cell proliferation in response to adhesive signaling. The growth inhibitory function of Merlin …

Simple Summary Although great breakthroughs have been made in cancer treatment
following the development of targeted therapy and immune therapy, resistance against anti …

The Hippo network is a major conserved growth suppressor pathway that participates in
organ size control during development and prevents tumour formation during adult …

Since cancer is one of the leading causes of death worldwide, there is an urgent need to find
better treatments. Currently, the use of chemotherapeutics remains the predominant option …

Inhibition of proliferation by cell‐to‐cell contact is essential for tissue organization, and its
disruption contributes to tumorigenesis. The FERM domain protein Merlin, encoded by the …

The Hippo pathway plays a key role in controlling organ growth in many animal species and
its deregulation is associated with different types of cancer. Understanding the regulation of …

Colorectal cancer (CRC) is one the most frequently diagnosed neoplastic diseases
worldwide. Currently, aside from traditional chemotherapy, advanced CRCs are treated with …

Chemotherapy is one of the major treatments for cancer patients. Although
chemotherapeutic drugs can sometimes effectively suppress tumor growth in cancer …

Objectives Paclitaxel (PTX) is frequently used in the clinical treatment of solid tumors. But the
PTX-resistance is a great obstacle in cancer treatment. Exploration of the mechanisms of …