Role of sleep deprivation in immune-related disease risk and outcomes
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …
Melatonin and inflammation—Story of a double‐edged blade
R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Aging, melatonin, and the pro-and anti-inflammatory networks
R Hardeland - International journal of molecular sciences, 2019 - mdpi.com
Aging and various age-related diseases are associated with reductions in melatonin
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …
[HTML][HTML] NF-κβ: a potential target in the management of vascular complications of diabetes
SV Suryavanshi, YA Kulkarni - Frontiers in pharmacology, 2017 - frontiersin.org
Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …
plays key role in pathogenesis of vascular complications of diabetes. Persistent …
Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets
S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …
Melatonin: a versatile protector against oxidative DNA damage
Oxidative damage to DNA has important implications for human health and has been
identified as a key factor in the onset and development of numerous diseases. Thus, it is …
identified as a key factor in the onset and development of numerous diseases. Thus, it is …
Melatonin: buffering the immune system
A Carrillo-Vico, PJ Lardone… - International journal of …, 2013 - mdpi.com
Melatonin modulates a wide range of physiological functions with pleiotropic effects on the
immune system. Despite the large number of reports implicating melatonin as an …
immune system. Despite the large number of reports implicating melatonin as an …
Insulin signaling pathway and related molecules: role in neurodegeneration and Alzheimer's disease
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its major
pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from …
pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from …
Mesenchymal stromal cell-derived exosomes ameliorate peripheral neuropathy in a mouse model of diabetes
B Fan, C Li, A Szalad, L Wang, W Pan, R Zhang… - Diabetologia, 2020 - Springer
Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
[HTML][HTML] A review on the potential of Resveratrol in prevention and therapy of diabetes and diabetic complications
DD Huang, G Shi, Y Jiang, C Yao, C Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a major world health problem and one of the most studied
diseases, which are highly prevalent in the whole world, it is frequently associated with …
diseases, which are highly prevalent in the whole world, it is frequently associated with …