[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
H Savoji, MH Mohammadi, N Rafatian, MK Toroghi… - Biomaterials, 2019 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
[HTML][HTML] Cohort-based long-term ozone exposure-associated mortality risks with adjusted metrics: a systematic review and meta-analysis
Long-term ozone (O 3) exposure may lead to non-communicable diseases and increase
mortality risk. However, cohort-based studies are relatively rare, and inconsistent exposure …
mortality risk. However, cohort-based studies are relatively rare, and inconsistent exposure …
Outdoor air pollution and new-onset airway disease. An official American Thoracic Society workshop report
GD Thurston, JR Balmes, E Garcia… - Annals of the …, 2020 - atsjournals.org
Although it is well accepted that air pollution exposure exacerbates preexisting airway
disease, it has not been firmly established that long-term pollution exposure increases the …
disease, it has not been firmly established that long-term pollution exposure increases the …
Composition of air pollution particles and oxidative stress in cells, tissues, and living systems
AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …
air pollution particles and human morbidity and mortality. Production of oxidants, either …
A critical review of approaches and limitations of inhalation bioavailability and bioaccessibility of metal (loid) s from ambient particulate matter or dust
Inhalation of metal (loid) s in ambient particulate matter (APM) represents a significant
exposure pathway to humans. Although exposure assessment associated with this pathway …
exposure pathway to humans. Although exposure assessment associated with this pathway …
Ambient particle inhalation and the cardiovascular system: potential mechanisms.
Well-documented air pollution episodes throughout recent history have led to deaths among
individuals with cardiovascular and respiratory disease. Although the components of air …
individuals with cardiovascular and respiratory disease. Although the components of air …
Effects of metals within ambient air particulate matter (PM) on human health
LC Chen, M Lippmann - Inhalation toxicology, 2009 - Taylor & Francis
We review literature providing insights on health-related effects caused by inhalation of
ambient air particulate matter (PM) containing metals, emphasizing effects associated with in …
ambient air particulate matter (PM) containing metals, emphasizing effects associated with in …
Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children
L Liu, R Poon, L Chen, AM Frescura… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Air pollution is associated with respiratory symptoms, lung function decrements,
and hospitalizations. However, there is little information about the influence of air pollution …
and hospitalizations. However, there is little information about the influence of air pollution …
Toxicological and epidemiological studies of cardiovascular effects of ambient air fine particulate matter (PM2.5) and its chemical components: Coherence and public …
M Lippmann - Critical reviews in toxicology, 2014 - Taylor & Francis
Recent investigations on PM2. 5 constituents' effects in community residents have
substantially enhanced our knowledge on the impacts of specific components, especially the …
substantially enhanced our knowledge on the impacts of specific components, especially the …
Synergistic and antagonistic interactions among the particulate matter components in generating reactive oxygen species based on the dithiothreitol assay
We assessed the interactions among the particulate matter (PM) components in generating
the reactive oxygen species (ROS) based on a dithiothreitol (DTT) assay. We started with the …
the reactive oxygen species (ROS) based on a dithiothreitol (DTT) assay. We started with the …