The role of radiotherapy in ophthalmic practice continues to grow. This growth has seen an
expansion of indications for radiotherapy, a refinement of the modalities that can be used …

Objective: To describe platinum-based chemotherapy combined with local treatment
modalities as an alternative to external beam radiotherapy for intraocular retinoblastoma …

Background. To review the currently available therapeutic modalities for radiation
retinopathy (RR), including newer investigational interventions directed towards specific …

Clinical, pathological and experimental studies of radiation retinopathy confirm that the
primary vascular event is endothelial cell loss and capillary closure. Pericytes are less …

Purpose: To investigate the risk of radiation-induced retinopathy according to total radiation
dose and fraction size, based on both retrospective and prospectively collected data …

Radiotherapy is associated with a broad spectrum of early and late normal tissue injury. It is
a basic clinical observation that even within a group of identically treated patients large …

Objective To identify the risk factors that lead to the development of radiation retinopathy
following plaque radiotherapy for posterior uveal melanoma. Radiation retinopathy is a …

Hypoxia causes increased expression of several proteins that have the potential to promote
neovascularization. Vascular endothelial growth factor (VEGF) is up‐regulated by hypoxia in …

PURPOSE: The purpose of this study was to determine factors associated with the
development of radiation retinopathy in a large series of patients with head-and-neck …

PURPOSE: To determine risk factors, occurrence rate, management, and outcome of
proliferative radiation retinopathy (PRR) after plaque radiotherapy for uveal melanoma …