Cellular and extracellular components in tumor microenvironment and their application in early diagnosis of cancers
R Wei, S Liu, S Zhang, L Min… - Analytical Cellular …, 2020 - Wiley Online Library
Tumors are surrounded by complex environmental components, including blood and lymph
vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and …
vessels, fibroblasts, endothelial cells, immune cells, cytokines, extracellular vesicles, and …
Nucleic acids analysis
Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and
express genetic information, which play central roles in diverse cellular events and diseases …
express genetic information, which play central roles in diverse cellular events and diseases …
A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples
The utility of mechanical metamaterials for biomedical applications has seldom been
explored. Here we show that a metamaterial that is mechanically responsive to antibody …
explored. Here we show that a metamaterial that is mechanically responsive to antibody …
Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy
Current technologies to measure drug–target interactions require complex processing and
invasive tissue biopsies, limiting their clinical utility for cancer treatment monitoring. Here we …
invasive tissue biopsies, limiting their clinical utility for cancer treatment monitoring. Here we …
Intracellular entropy‐driven multi‐bit DNA computing for tumor progression discrimination
M Bai, F Chen, X Cao, Y Zhao, J Xue… - Angewandte Chemie …, 2020 - Wiley Online Library
Tumor progressions such as metastasis are complicated events that involve abnormal
expression of different miRNAs and enzymes. Monitoring these biomolecules in live cells …
expression of different miRNAs and enzymes. Monitoring these biomolecules in live cells …
[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules
W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …
genetic material, but also serves as well-defined functional material, for example, building …
Enhancing the sensitivity of photoelectrochemical DNA biosensing using plasmonic DNA barcodes and differential signal readout
Photoelectrochemical biosensors hold great promise for sensitive bioanalysis; however,
similar to their electrochemical analogues, they are highly affected by the variable …
similar to their electrochemical analogues, they are highly affected by the variable …
Advancing breast cancer heterogeneity analysis: Insights from genomics, transcriptomics and proteomics at bulk and single-cell levels
Z Zhu, L Jiang, X Ding - Cancers, 2023 - mdpi.com
Simple Summary This review discusses the heterogeneity of breast cancer and strategies to
understand it using multi-omics profiling methods at the traditional bulk and single-cell …
understand it using multi-omics profiling methods at the traditional bulk and single-cell …
Exosome-templated nanoplasmonics for multiparametric molecular profiling
Exosomes are nanoscale vesicles distinguished by characteristic biophysical and
biomolecular features; current analytical approaches, however, remain univariate. Here, we …
biomolecular features; current analytical approaches, however, remain univariate. Here, we …
Progress in biomedical applications of tetrahedral framework nucleic acid-based functional systems
The past decades have witnessed the development of DNA nanotechnology and the
emergence of various spatial DNA nanostructures, from two-dimensions to three …
emergence of various spatial DNA nanostructures, from two-dimensions to three …