DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …

Hepatocellular carcinoma (HCC) is a deadly tumour whose causative agents are generally
well known, but whose pathogenesis remains poorly understood. Nevertheless, key genetic …

The incidence of lymphoma has gradually increased over previous decades, and it ranks
among the ten most prevalent cancers worldwide. With the development of targeted …

Studies over the past four decades have elucidated the role of Wnt/β-catenin mediated
regulation in cell proliferation, differentiation and migration. These processes are …

Chromatin conformation regulates gene expression and thus, constant remodeling of
chromatin structure is essential to guarantee proper cell function. To gain insight into the …

Systemic lupus erythematosus (SLE) is an autoimmune disorder that is characterized by
autoantibody production and dysregulated immune cell activation. Although the exact …

Radiation therapy has been increasingly employed as a tool to cure and palliate majority of
solid tumors. Although radiotherapy has shown promising results in preserving structure and …

Peroxisome proliferator‐activated receptor alpha (PPARA) is the molecular target of fibrates
commonly used to treat dyslipidemia and diabetes. Recently, the potential role of PPARA in …

DNA methylation is an epigenetic modification with wide-ranging consequences across the
life of an organism. This modification can be stable, persisting through development despite …