High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

AA Yurchenko, TE Deniskova, NS Yudin, AV Dotsev… - BMC genomics, 2019 - Springer
Background Domestication and centuries of selective breeding have changed genomes of
sheep breeds to respond to environmental challenges and human needs. The genomes of …

Interaction between cigarette smoke and human papillomavirus 16 E6/E7 oncoproteins to induce SOD2 expression and DNA damage in head and neck cancer

D Carrillo-Beltrán, JC Osorio, R Blanco, C Oliva… - International Journal of …, 2023 - mdpi.com
Even though epidemiological studies suggest that tobacco smoking and high-risk human
papillomavirus (HR-HPV) infection are mutually exclusive risk factors for developing head …

Physiological DNA damage promotes functional endoreplication of mammary gland alveolar cells during lactation

R Molinuevo, J Menendez, K Cadle, N Ariqat… - Nature …, 2024 - nature.com
Lactation insufficiency affects many women worldwide. During lactation, a large portion of
mammary gland alveolar cells become polyploid, but how these cells balance the …

SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation

L Sanchez, J Epps, S Wall, C McQueen… - Cell Death & …, 2023 - nature.com
The functionally differentiated mammary gland adapts to extreme levels of stress from
increased demand for energy by activating specific protective mechanisms to support …

In Silico-Analysis of the Multi-Omics Data Identified the Ataxia Telangiectasia Mutated Gene as a Potential Biomarker of Breast Invasive Carcinoma

U Karamat, S Ejaz, Y Hameed - Genetic Testing and Molecular …, 2021 - liebertpub.com
Background: The elevated global burden of breast invasive carcinoma (BRIC) and lack of
appropriate biomarkers for its early detection and treatment requires extensive investigation …

Investigating the Role of KAP1 in Mammary Gland Development

N Govindrajan - 2024 - prism.ucalgary.ca
KAP1 controls cell fate specification of spermatogonial, skeletal, and hematopoietic
progenitors, and promotes embryonic and breast cancer stem cell renewal. It regulates cell …

[HTML][HTML] ATM is necessary for IGF-1R expression in the murine mammary gland

KD Brown, LM Dyer - Journal of Molecular and Clinical Medicine, 2020 - imrpress.com
Ataxia-telangiectasia mutated is a protein kinase that is critical for the maintenance of
genomic stability and proper cellular response to redox imbalance. Previous studies indicate …

[HTML][HTML] Blood transcriptome analysis and identification of genes associated with supernumerary teats in Chinese Holstein cows

QZ Chen, MY Yang, XQ Liu, JN Zhang, SY Mi… - Journal of Dairy …, 2022 - Elsevier
In dairy cows, supernumerary teats (SNT) are not desired as they are considered a
repository for bacteria; thus, SNT are a risk factor for mastitis. Supernumerary teats are a …