• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Background Ceftobiprole is a cephalosporin that may be effective for treating complicated
Staphylococcus aureus bacteremia, including methicillin-resistant S. aureus. Methods In this …

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged,
disseminated globally and become a leading cause of bacterial infections in both health …

Background Precise estimates of mortality in Staphylococcus aureus bacteraemia (SAB) are
important to convey prognosis and guide the design of interventional studies. Objectives We …

Background—Infective endocarditis is a potentially lethal disease that has undergone major
changes in both host and pathogen. The epidemiology of infective endocarditis has become …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Infective endocarditis is defined by a focus of infection within the heart and is a feared
disease across the field of cardiology. It is frequently acquired in the health care setting, and …

Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …