Periodontitis and its inflammatory changes linked to various systemic diseases: a review of its underlying mechanisms

R Bhuyan, SK Bhuyan, JN Mohanty, S Das, N Juliana… - Biomedicines, 2022 - mdpi.com
Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …

Role of host and pathogen-derived microRNAs in immune regulation during infectious and inflammatory diseases

K Chandan, M Gupta, M Sarwat - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …

Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk

G Isola, S Santonocito, A Distefano… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Objective Recent emerging evidence has shown that microRNA
(miRNAs) is involved in several epigenetic processes linked with periodontitis, increased …

Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential

KT Jurdziński, J Potempa, AM Grabiec - Clinical epigenetics, 2020 - Springer
Epigenetic mechanisms, namely DNA and histone modifications, are critical regulators of
immunity and inflammation which have emerged as potential targets for immunomodulating …

Diabetes mellitus promotes susceptibility to periodontitis—novel insight into the molecular mechanisms

M Zhao, Y Xie, W Gao, C Li, Q Ye, Y Li - Frontiers in endocrinology, 2023 - frontiersin.org
Diabetes mellitus is a main risk factor for periodontitis, but until now, the underlying
molecular mechanisms remain unclear. Diabetes can increase the pathogenicity of the …

Innate and adaptive immune evasion by dengue virus

MF Lee, GZ Voon, HX Lim, ML Chua… - Frontiers in Cellular and …, 2022 - frontiersin.org
Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: biogenesis, mechanisms, and delivery nanocarriers

A Deka Dey, S Yousefiasl, A Kumar… - Bioengineering & …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) as therapeutic agents have attracted increasing interest in the past
decade owing to their significant effectiveness in treating a wide array of ailments. These …

Salivary small extracellular vesicles associated miRNAs in periodontal status—A pilot study

P Han, PM Bartold, C Salomon, S Ivanovski - International journal of …, 2020 - mdpi.com
This pilot study aims to investigate whether salivary small extracellular vesicle (sEV)-
associated microRNAs could act as potential biomarkers for periodontal disease status …

Genetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis

H Luo, D Chen, R Li, R Li, Y Teng, Y Cao, X Zou… - Journal of …, 2023 - Springer
Biofilm-related diseases are a group of diseases that tolerate antimicrobial chemotherapies
and therefore are refractory to treatment. Periodontitis, a non-device chronic biofilm disease …

[HTML][HTML] Periodontitis and oral cancer-current concepts of the etiopathogenesis

S Irani, I Barati, M Badiei - Oncology reviews, 2020 - ncbi.nlm.nih.gov
Gingival tissues are attacked by oral pathogens which can induce inflammatory reactions.
The immune-inflammatory responses play essential roles in the patient susceptibility to …