Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot
disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to …

Objective To investigate neurodegenerative and inflammatory biomarkers in people with
amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression …

Amyotrophic lateral sclerosis (ALS) is a grievous neurodegenerative disease whose survival
is limited to only a few years. In spite of intensive research to discover the underlying …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease
characterized by the progressive loss of motor neurons, for which current treatment options …

The most common inherited cause of two genetically and clinico-pathologically overlapping
neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal …

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with an extremely
heterogeneous clinical and genetic phenotype. In our efforts to find therapies for ALS, the …

Massive GGGGCC (G4C2) repeat expansion in C9orf72 and the resulting loss of C9orf72
function are the key features of~ 50% of inherited amyotrophic lateral sclerosis and …

Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative
disease. Despite decades of research and many new insights into disease biology over the …

RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways
underpinning biological processes are affected by the events governing the RNA life cycle …