The eye is a complex organ consisting of several protective barriers and particular defense
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …

Topical route of administration is the most commonly used method for the treatment of
ophthalmic diseases. However, presence of several layers of permeation barriers starting …

The topical route is the most frequent and preferred way to deliver drugs to the eye.
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …

Research advancements in pharmaceutical sciences have led to the development of new
strategies in drug delivery to anterior segment. Designing a new delivery system that can …

Novel MOF-based polymer nanocomposite films were successfully prepared using Zr-based
UiO-67 as a metal–organic framework (MOF) and polyurethane (PU) as a polymeric matrix …

Niosomes are increasingly explored for enhancing drug penetration and retention in ocular
tissues for both posterior and anterior eye delivery. They have been employed in …

Glaucoma, a chronic disease of elevated intraocular pressure, is considered as the first
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …

Metal–organic frameworks (MOFs) have been evaluated as potential nanocarriers for
intraocular incorporation of brimonidine tartrate to treat chronic glaucoma. Experimental …

Glaucoma is the second leading cause of blindness worldwide. Even though significant
advances have been made in its management, currently available antiglaucoma therapies …

With the recent advancement in the field of ocular therapy, drug delivery approaches have
been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the …