Cells tightly regulate mRNA processing, localization, and stability to ensure accurate gene
expression in diverse cellular states and conditions. Most of these regulatory steps have …

Encapsulation and compartmentalization are fundamental to the evolution of cellular life, but
they also pose a challenge: how to partition the molecules that perform biological functions …

SecA belongs to the large class of ATP ases that use the energy of ATP hydrolysis to
perform mechanical work resulting in protein translocation across membranes, protein …

SecA, an ATPase known to posttranslationally translocate secretory proteins across the
bacterial plasma membrane, also binds ribosomes, but the role of SecA's ribosome …

Almost all outer membrane proteins (OMPs) in Gram-negative bacteria contain a β-barrel
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …

The formation of disulfide bonds is critical to the folding of many extracytoplasmic proteins in
all domains of life. With the discovery in the early 1990s that disulfide bond formation is …

The universally conserved Sec system is the primary method cells utilize to transport
proteins across membranes. Until recently, measuring the activity—a prerequisite for …

The outer-membrane of Gram-negative bacteria is critical for surface adhesion,
pathogenicity, antibiotic resistance and survival. The major constituent–hydrophobic β-barrel …

Abstract (2S)-Sakuranetin is a 7-O-methylflavonoid that has anticancer, antiviral, and
antimicrobial activities. Methylation process is involved in biosynthesizing (2S)-sakuranetin …

Background Engineering bacterial strains to redirect the metabolism towards the production
of a specific product has enabled the development of industrial biotechnology. However …