Amyotrophic lateral sclerosis (ALS) is the most common form of human motor neuron
disease. It is characterized by the progressive degeneration of upper and lower motor …

In the last few years, our understanding of disease molecular mechanisms underpinning
ALS has advanced greatly, allowing the first steps in translating into clinical practice novel …

Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by progressive motor function and muscle mass loss. Despite extensive research in the field …

Background and objectives: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative
disease characterized by progressive motor neuron degeneration resulting in loss of muscle …

A combination of multiple genetic and environmental factors appear to be required to trigger
the onset of amyotrophic lateral sclerosis (ALS). Early life environmental exposures have …

Introduction Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative
disease affecting motor neurons. Currently, ALS is conceived as the result of the interaction …

One of the most robust approaches to the prediction of causal driver genes of complex
diseases is to apply reverse engineering methods to infer a gene regulatory network (GRN) …

The transgenic SOD1G93A mouse model is the most widely used animal model of
amyotrophic lateral sclerosis (ALS), a fatal disease of motor neuron degeneration. While …

Background: Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative
condition. In ALS, wasting of skeletal muscle causes weakness, paralysis and ultimately …

Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized
by progressive motor function and muscle mass loss. Despite extensive research in the field …