Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Given the increasing evidence indicates that many pathological conditions are associated
with elevated reactive oxygen species (ROS) levels, there have been growing research …

Elevated levels of reactive oxygen species (ROS) have commonly been implicated in a
variety of diseases, including cancer, inflammation, and neurodegenerative diseases. In …

Iron is an essential dietary element. However, the ability of iron to cycle between oxidized
and reduced forms also renders it capable of contributing to free radical formation, which …

Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …

Cancer stem cells (CSCs) are a distinct subpopulation of tumor cells with stem cell-like
features. Able to initiate and sustain tumor growth and mostly resistant to anti-cancer …

Various boron-containing drugs have been approved for clinical use over the past two
decades, and more are currently in clinical trials. The increasing interest in boron-containing …

Radiosensitizers are agents capable of amplifying injury to tumor tissues by enhancing DNA
damage and fortifying production of radical oxygen species (ROS). The use of such …

Boronic acid (or ester) is a well-known temporary masking group for developing anticancer
prodrugs responsive to tumoral reactive oxygen species (ROS), but their clinic application is …

Cancer cells produce elevated levels of reactive oxygen species, which has been used to
design cancer specific prodrugs. Their activation relies on at least a bimolecular process, in …