The biological function and significance of CD74 in immune diseases
H Su, N Na, X Zhang, Y Zhao - Inflammation Research, 2017 - Springer
Abstract CD74 (MHC class II invariant chain, Ii) is a non-polymorphic type II transmembrane
glycoprotein. It is clear that, in addition to be an MHC class II chaperone, CD74 has a …
glycoprotein. It is clear that, in addition to be an MHC class II chaperone, CD74 has a …
[HTML][HTML] Role of MIF cytokine/CD74 receptor pathway in protecting against injury and promoting repair
Wound healing after an injury is essential for life. An in-depth understanding of the healing
process is necessary to ultimately improve the currently limited treatment options for patients …
process is necessary to ultimately improve the currently limited treatment options for patients …
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
DE Harrison, R Strong, P Reifsnyder, N Kumar… - Aging cell, 2021 - Wiley Online Library
In genetically heterogeneous mice produced by the CByB6F1 x C3D2F1 cross, the “non‐
feminizing” estrogen, 17‐α‐estradiol (17aE2), extended median male lifespan by 19%(p< …
feminizing” estrogen, 17‐α‐estradiol (17aE2), extended median male lifespan by 19%(p< …
The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery
Acute kidney injury (AKI) represents the most frequent complication after cardiac surgery.
Macrophage migration inhibitory factor (MIF) is a stress-regulating cytokine that was shown …
Macrophage migration inhibitory factor (MIF) is a stress-regulating cytokine that was shown …
Single-cell expression atlas reveals cell heterogeneity in the creeping fat of Crohn's disease
W Shu, Y Wang, C Li, L Zhang… - Inflammatory Bowel …, 2023 - academic.oup.com
Abstract Background Creeping fat (CrF) has been recognized to play a positive role in
Crohn's disease (CD) progression, yet the cellular compositions within mesenteric adipose …
Crohn's disease (CD) progression, yet the cellular compositions within mesenteric adipose …
Macrophage migration inhibitory factor regulates U1 small nuclear RNP immune complex–mediated activation of the NLRP3 Inflammasome
MS Shin, Y Kang, ER Wahl, HJ Park… - Arthritis & …, 2019 - Wiley Online Library
Objective High‐expression alleles of macrophage migration inhibitory factor (MIF) are linked
genetically to the severity of systemic lupus erythematosus (SLE). The U1 small nuclear …
genetically to the severity of systemic lupus erythematosus (SLE). The U1 small nuclear …
[HTML][HTML] The role of CD74 in cardiovascular disease
QL Li, J Tang, L Zhao, A Ruze, XF Shan… - Frontiers in …, 2023 - frontiersin.org
Leukocyte differentiation antigen 74 (CD74), also known as invariant chain, is a molecular
chaperone of major histocompatibility complex class II (MHC II) molecules involved in …
chaperone of major histocompatibility complex class II (MHC II) molecules involved in …
Stress promotes the infiltration of peripheral immune cells to the brain
EM Medina-Rodriguez, D Han, J Lowell… - Brain, behavior, and …, 2023 - Elsevier
Immune cells and the brain have a privileged interaction. Here, we report changes in the
hippocampal immune microenvironment at the single cell level after stress, uncovering the …
hippocampal immune microenvironment at the single cell level after stress, uncovering the …
[HTML][HTML] Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture
The human malaria parasite Plasmodium falciparum is responsible for the majority of
mortality and morbidity caused by malaria infection and differs from other human malaria …
mortality and morbidity caused by malaria infection and differs from other human malaria …
[HTML][HTML] A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity
PV Tilstam, G Pantouris, M Corman, M Andreoli… - Journal of Biological …, 2019 - ASBMB
Cytokine macrophage migration inhibitory factor-2 (MIF-2 or D-dopachrome tautomerase) is
a recently characterized second member of the MIF cytokine superfamily in mammalian …
a recently characterized second member of the MIF cytokine superfamily in mammalian …