Abstract The 4, 4′-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally
used as a potent anti-bacterial agent in clinical management of leprosy. For decades …

Dose-limiting toxicities (DLTs) are severe adverse effects that define the maximum tolerated
dose of a cancer drug. In addition to the specific mechanisms of each drug, common …

Background and objective Pulmonary fibrosis (PF) is a chronic and progressive respiratory
disease representing the final stage of lung inflammatory disorders. Reactive oxygen …

Aims Allergic rhinitis (AR), a major chronic inflammatory disease of the respiratory system, is
a public health issue because of its substantial negative impact on quality of life and work …

Purpose Integrins αv are key molecules in the pathogenesis of fibrosis in multiple organs. To
assess the potential utility of integrin αvβ3 imaging for idiopathic pulmonary fibrosis (IPF), we …

Background Idiopathic pulmonary fibrosis (IPF) is a pulmonary fibrotic disease characterized
by a poor prognosis, which its pathogenesis involves the accumulation of abnormal fibrous …

Fibrosis, the excessive deposition of fibrous connective tissue in an organ in response to
injury, is a pathological condition affecting many individuals worldwide. Fibrosis causes the …

20 (R)-25-methoxyl-dammarane-3β, 12β, 20-triol (25-OCH3–PPD, AD-1) is a dammarane
ginsenoside that is isolated from Panax notoginseng. The present study aimed to explore its …

Abstract Serum heme oxygenase (HO)-1 level has been reported as a clinically reliable
diagnostic biomarker for acute exacerbation of interstitial lung disease (ILD); however, its …

Reactive oxygen species (ROSs) are byproducts of normal cellular metabolism and play
pivotal roles in various physiological processes. Disruptions in the balance between ROS …