Pentagalloyl glucose and its functional role in vascular health: Biomechanics and drug-delivery characteristics

SS Patnaik, DT Simionescu, CJ Goergen… - Annals of biomedical …, 2019 - Springer
Pentagalloyl glucose (PGG) is an elastin-stabilizing polyphenolic compound that has
significant biomedical benefits, such as being a free radical sink, an anti-inflammatory agent …

The Potential of Deep Learning to Advance Clinical Applications of Computational Biomechanics

GA Truskey - Bioengineering, 2023 - mdpi.com
When combined with patient information provided by advanced imaging techniques,
computational biomechanics can provide detailed patient-specific information about …

Mechanical and geometrical determinants of wall stress in abdominal aortic aneurysms: A computational study

D Azar, D Ohadi, A Rachev, JF Eberth, MJ Uline… - Plos one, 2018 - journals.plos.org
An aortic aneurysm (AA) is a focal dilatation of the aortic wall. Occurrence of AA rupture is an
all too common event that is associated with high levels of patient morbidity and mortality …

Cerebral aneurysm rupture status classification using statistical and machine learning methods

N Amigo, A Valencia, W Wu… - Proceedings of the …, 2021 - journals.sagepub.com
Morphological characterization and fluid dynamics simulations were carried out to classify
the rupture status of 71 (36 unruptured, 35 ruptured) patient specific cerebral aneurysms …

A predictive analysis of wall stress in abdominal aortic aneurysms using a neural network model

B Rengarajan, SS Patnaik… - Journal of …, 2021 - asmedigitalcollection.asme.org
Rupture risk assessment of abdominal aortic aneurysms (AAAs) by means of quantifying
wall stress is a common biomechanical strategy. However, the clinical translation of this …

Application of fluid–structure interaction methods to estimate the mechanics of rupture in asian abdominal aortic aneurysms

T Canchi, A Saxena, EYK Ng, ECH Pwee… - Bionanoscience, 2018 - Springer
Abdominal aortic aneurysms (AAAs) occur because of dilation of the infra-renal aorta to
more than 150% of its initial diameter. Progression to rupture is aided by several …

Geometry and flow in ascending aortic aneurysms are influenced by left ventricular outflow tract orientation: Detecting increased wall shear stress on the outer curve of …

MY Salmasi, S Pirola, S Mahuttanatan… - The Journal of Thoracic …, 2023 - Elsevier
Background The geometrical characterization of ascending thoracic aortic aneurysms in
clinical practice is limited to diameter measurements. Despite growing interest in …

Impact of Geometric Attributes on Abdominal Aortic Aneurysm Rupture Risk: An In Vivo FSI‐Based Study

X Wang, MH Ghayesh, J Li, A Kotousov… - International Journal …, 2024 - Wiley Online Library
Reported in this paper is a cutting‐edge computational investigation into the influence of
geometric characteristics on abdominal aortic aneurysm (AAA) rupture risk, beyond the …

Biomechanical restoration potential of pentagalloyl glucose after arterial extracellular matrix degeneration

SS Patnaik, S Piskin, NR Pillalamarri, G Romero… - Bioengineering, 2019 - mdpi.com
The objective of this study was to quantify pentagalloyl glucose (PGG) mediated
biomechanical restoration of degenerated extracellular matrix (ECM). Planar biaxial tensile …

Stress analysis in AAA does not predict rupture location correctly in patients with intraluminal thrombus

F Lorandon, S Rinckenbach, N Settembre… - Annals of Vascular …, 2022 - Elsevier
Background A biomechanical approach to the rupture risk of an abdominal aortic aneurysm
could be a solution to ensure a personalized estimate of this risk. It is still difficult to know in …