Implantable intracortical microelectrodes: reviewing the present with a focus on the future

Y Wang, X Yang, X Zhang, Y Wang… - Microsystems & …, 2023 - nature.com
Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Recent progress in materials chemistry to advance flexible bioelectronics in medicine

G Balakrishnan, J Song, C Mou… - Advanced …, 2022 - Wiley Online Library
Designing bioelectronic devices that seamlessly integrate with the human body is a
technological pursuit of great importance. Bioelectronic medical devices that reliably and …

Full-bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene microtransistor depth neural probes

A Bonaccini Calia, E Masvidal-Codina… - Nature …, 2022 - nature.com
Mapping the entire frequency bandwidth of brain electrophysiological signals is of
paramount importance for understanding physiological and pathological states. The ability …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

A review on mechanical considerations for chronically-implanted neural probes

A Lecomte, E Descamps… - Journal of neural …, 2018 - iopscience.iop.org
This review intends to present a comprehensive analysis of the mechanical considerations
for chronically-implanted neural probes. Failure of neural electrical recordings or stimulation …

Flexible, penetrating brain probes enabled by advances in polymer microfabrication

A Weltman, J Yoo, E Meng - Micromachines, 2016 - mdpi.com
The acquisition of high-fidelity, long-term neural recordings in vivo is critically important to
advance neuroscience and brain–machine interfaces. For decades, rigid materials such as …

Techniques and considerations in the microfabrication of Parylene C microelectromechanical systems

J Ortigoza-Diaz, K Scholten, C Larson, A Cobo… - Micromachines, 2018 - mdpi.com
Parylene C is a promising material for constructing flexible, biocompatible and corrosion-
resistant microelectromechanical systems (MEMS) devices. Historically, Parylene C has …

Flexible electrodes for brain–computer interface system

J Wang, T Wang, H Liu, K Wang, K Moses… - Advanced …, 2023 - Wiley Online Library
Brain–computer interface (BCI) has been the subject of extensive research recently.
Governments and companies have substantially invested in relevant research and …

Neural tissue-microelectrode interaction: Brain micromotion, electrical impedance, and flexible microelectrode insertion

N Sharafkhani, AZ Kouzani, SD Adams, JM Long… - Journal of Neuroscience …, 2022 - Elsevier
Insertion of a microelectrode into the brain to record/stimulate neurons damages neural
tissue and blood vessels and initiates the brain's wound healing response. Due to the large …

Fluidic microactuation of flexible electrodes for neural recording

F Vitale, DG Vercosa, AV Rodriguez, SS Pamulapati… - Nano …, 2018 - ACS Publications
Soft and conductive nanomaterials like carbon nanotubes, graphene, and nanowire
scaffolds have expanded the family of ultraflexible microelectrodes that can bend and flex …