Lipid composition determines membrane properties, and cholesterol plays a major role in
this determination as it regulates membrane fluidity and permeability, as well as induces the …

Abstract Site-Directed Spin Labelling (SDSL) technique is based on the attachment of a
paramagnetic label onto a specific position of a protein (or other bio-molecules) and the …

The maintenance of a fluid lipid bilayer is key for membrane integrity and cell viability. We
are only beginning to understand how eukaryotic cells sense and maintain the characteristic …

Since its inception more than thirty years ago, electroformation has become the most
commonly used method for growing giant unilamellar vesicles (GUVs). Although the method …

The intracellular environment is crowded with macromolecules, including sugars, proteins
and nucleic acids. In the cytoplasm, crowding effects are capable of excluding up to 40% of …

Short-lived cell membrane complexes play a key role in regulating cell signaling and
communication. Many of these complexes are formed based on low-affinity and transient …

It has been a long journey from Pliny the Elder (23–79 AD) to the FDA approval of the first
injectable Nanomedicine in 1997. It has been a journey powered by intellectual curiosity …

Lutein, zeaxanthin, and meso-zeaxanthin (a steroisomer of zeaxanthin) are macular
pigments. They modify the physical properties of the lipid bilayers in a manner similar to …

The most unique feature of the eye lens fiber-cell plasma membrane is its extremely high
cholesterol content. Cholesterol saturates the bulk phospholipid bilayer and induces …

The effect of lyophilization and rehydration medium on a liposome system for conjugated
linoleic acid (CLA) delivery was studied. Liposomes were prepared by ethanol injection …