This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Aerobic exercise training leads to cardiovascular changes that markedly increase aerobic
power and lead to improved endurance performance. The functionally most important …

A systematic meta-regression analysis of the effects of acute hypoxia on the performance of
central executive and non-executive tasks, and the effects of the moderating variables …

This review addresses the pathophysiology and treatment of hemorrhagic shock–a condition
produced by rapid and significant loss of intravascular volume, which may lead sequentially …

Of all the chemical elements, oxygen is the most vital to the human body. The brain is the
most sensitive organ to oxygen deprivation (hypoxia), which, over an extended period, can …

Skeletal muscle blood flow is closely coupled to metabolic demand, and its regulation is
believed to be mainly the result of the interplay of neural vasoconstrictor activity and locally …

During exercise, oxygen delivery to skeletal muscle is elevated to meet the increased
oxygen demand. The increase in blood flow to skeletal muscle is achieved by vasodilators …

Hypoxia, characterized by reduced oxygen concentration, is a significant stressor that affects
the survival of aerobic species and plays a prominent role in cardiovascular diseases. From …

Nocebo and placebo effects have been found to modulate several neurochemical systems,
such as cholecystokinin, endogenous opioids, and endocannabinoids. Here we show that …