Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Understanding cell penetration of cyclic peptides

PG Dougherty, A Sahni, D Pei - Chemical Reviews, 2019 - ACS Publications
Approximately 75% of all disease-relevant human proteins, including those involved in
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …

Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Cyclic cell-penetrating peptides as efficient intracellular drug delivery tools

SE Park, MI Sajid, K Parang, RK Tiwari - Molecular pharmaceutics, 2019 - ACS Publications
Cyclic cell-penetrating peptides are relatively a newer class of peptides that have a huge
potential for the intracellular delivery of therapeutic agents aimed at treating challenging …

Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases

B Wang, X Chen, Z Chen, H Xiao, J Dong, Y Li… - … & Molecular Medicine, 2023 - nature.com
Gut microbial preparations are widely used in treating intestinal diseases but show mixed
success. In this study, we found that the therapeutic efficacy of A. muciniphila for dextran …

The recent advance of cell-penetrating and tumor-targeting peptides as drug delivery systems based on tumor microenvironment

Q Zhang, N Liu, J Wang, Y Liu, K Wang… - Molecular …, 2023 - ACS Publications
Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …

Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling

P Kubatka, L Koklesova, A Mazurakova… - Cancer and Metastasis …, 2024 - Springer
Cancer cell plasticity plays a crucial role in tumor initiation, progression, and metastasis and
is implicated in the multiple cancer defense mechanisms associated with therapy resistance …

Delivery of various cargos into cancer cells and tissues via cell-penetrating peptides: a review of the last decade

A Shoari, R Tooyserkani, M Tahmasebi, DWPM Löwik - Pharmaceutics, 2021 - mdpi.com
Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …

[HTML][HTML] Peptides as carriers of active ingredients: A review

C Nie, Y Zou, S Liao, Q Gao, Q Li - Current Research in Food Science, 2023 - Elsevier
Bioactive compounds are highly valuable in the fields of food and medicine, but their
application is limited due to easy deterioration after oral or skin administration. In recent …