Microglia regulation of synaptic plasticity and learning and memory
J Cornell, S Salinas, HY Huang… - Neural regeneration …, 2022 - journals.lww.com
Microglia are the resident macrophages of the central nervous system. Microglia possess
varied morphologies and functions. Under normal physiological conditions, microglia mainly …
varied morphologies and functions. Under normal physiological conditions, microglia mainly …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells
D Belov Kirdajova, J Kriska, J Tureckova… - Frontiers in cellular …, 2020 - frontiersin.org
A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
Brain cells continuously produce and release protons into the extracellular space, with the
rate of acid production corresponding to the levels of neuronal activity and metabolism …
rate of acid production corresponding to the levels of neuronal activity and metabolism …
The tripartite glutamatergic synapse
Astroglial cells were long considered as structural and metabolic supporting cells are which
do not directly participate in information processing in the brain. Discoveries of …
do not directly participate in information processing in the brain. Discoveries of …
Purinergic signaling orchestrating neuron-glia communication
P Agostinho, D Madeira, L Dias, AP Simões… - Pharmacological …, 2020 - Elsevier
This review discusses the evidence supporting a role for ATP signaling (operated by P 2 X
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading
H Martini-Stoica, AL Cole, DB Swartzlander… - Journal of Experimental …, 2018 - rupress.org
The progression of tau pathology in Alzheimer's disease follows a stereotyped pattern, and
recent evidence suggests a role of synaptic connections in this process. Astrocytes are well …
recent evidence suggests a role of synaptic connections in this process. Astrocytes are well …
Melanopsin for precise optogenetic activation of astrocyte‐neuron networks
S Mederos, A Hernández‐Vivanco, J Ramírez‐Franco… - Glia, 2019 - Wiley Online Library
Optogenetics has been widely expanded to enhance or suppress neuronal activity and it
has been recently applied to glial cells. Here, we have used a new approach based on …
has been recently applied to glial cells. Here, we have used a new approach based on …
ATP-mediated signalling in the central synapses
U Lalo, Y Pankratov - Neuropharmacology, 2023 - Elsevier
ATP released from the synaptic terminals and astrocytes can activate neuronal P2 receptors
at a variety of locations across the CNS. Although the postsynaptic ATP-mediated signalling …
at a variety of locations across the CNS. Although the postsynaptic ATP-mediated signalling …
Astrocytes, noradrenaline, α1-adrenoreceptors, and neuromodulation: evidence and unanswered questions
J Wahis, MG Holt - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Noradrenaline is a major neuromodulator in the central nervous system (CNS). It is released
from varicosities on neuronal efferents, which originate principally from the main …
from varicosities on neuronal efferents, which originate principally from the main …