Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies

E Molinaro, C Romei, A Biagini, E Sabini… - Nature Reviews …, 2017 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

[HTML][HTML] Therapeutic advances in anaplastic thyroid cancer: a current perspective

S Saini, K Tulla, AV Maker, KD Burman, BS Prabhakar - Molecular cancer, 2018 - Springer
Thyroid cancer incidence is increasing at an alarming rate, almost tripling every decade. In
2017, it was the fifth most common cancer in women. Although the majority of thyroid tumors …

Thyroid carcinoma, version 2.2022, NCCN clinical practice guidelines in oncology

RI Haddad, L Bischoff, D Ball, V Bernet… - Journal of the National …, 2022 - jnccn.org
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of
choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation …

2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer …

KC Bible, E Kebebew, J Brierley, JP Brito… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

[HTML][HTML] Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study

V Subbiah, RJ Kreitman, ZA Wainberg, JY Cho… - Annals of …, 2022 - Elsevier
Background Combined therapy with dabrafenib plus trametinib was approved in several
countries for treatment of BRAF V600E-mutant anaplastic thyroid cancer (ATC) based on an …

Open-label, single-arm, multicenter, phase II trial of lenvatinib for the treatment of patients with anaplastic thyroid cancer

LJ Wirth, MS Brose, EJ Sherman, L Licitra… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Anaplastic thyroid cancer (ATC), an aggressive malignancy, is associated with a
poor prognosis and an unmet need for effective treatment, especially for patients without …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

The revised clinical practice guidelines on the management of thyroid tumors by the Japan Associations of Endocrine Surgeons: Core questions and …

Y Ito, N Onoda, T Okamoto - Endocrine journal, 2020 - jstage.jst.go.jp
Abstract The Japan Associations of Endocrine Surgeons has developed the revised version
of the Clinical Practice Guidelines for Thyroid Tumors. This article describes the guidelines …

[HTML][HTML] Lenvatinib for anaplastic thyroid cancer

M Tahara, N Kiyota, T Yamazaki, N Chayahara… - Frontiers in …, 2017 - frontiersin.org
Background Lenvatinib has been approved by regulatory agencies in Japan, the United
States, and the European Union for treatment of radioiodine-refractory differentiated thyroid …

Advances in the management of anaplastic thyroid carcinoma: transforming a life-threatening condition into a potentially treatable disease

I Califano, A Smulever, F Jerkovich, F Pitoia - Reviews in Endocrine and …, 2024 - Springer
Anaplastic thyroid cancer (ATC) is an infrequent thyroid tumor that usually occurs in elderly
patients. There is often a history of previous differentiated thyroid cancer suggesting a …