Early detection of cancer

D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive… - Science, 2022 - science.org
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Recent advances in nanozymes: from matters to bioapplications

Y Ai, ZN Hu, X Liang, H Sun, H Xin… - Advanced Functional …, 2022 - Wiley Online Library
The manufacture of bionic materials to simulate the natural counterparts has attracted
extensive attention. As one of the subcategories of biomimetic materials, the development of …

Inorganic nanomaterials with rapid clearance for biomedical applications

X Wang, X Zhong, J Li, Z Liu, L Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …

Molecular imaging and disease theranostics with renal-clearable optical agents

P Cheng, K Pu - Nature Reviews Materials, 2021 - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

[HTML][HTML] Multifunctional gold nanoparticles: a novel nanomaterial for various medical applications and biological activities

X Hu, Y Zhang, T Ding, J Liu, H Zhao - Frontiers in Bioengineering …, 2020 - frontiersin.org
Nanotechnology has become a trending area in science and has made great advances with
the development of functional, engineered nanoparticles. Various metal nanoparticles have …

Nanozyme-enabled analytical chemistry

S Li, Y Zhang, Q Wang, A Lin, H Wei - Analytical Chemistry, 2021 - ACS Publications
In 2007, landmark research recognized ferromagnetic nanoparticles (Fe3O4 NPs) as the
substitute of horseradish peroxidase (HRP) for their alike catalytic ability to oxidize signal …

Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection

J Huang, X Chen, Y Jiang, C Zhang, S He, H Wang… - Nature Materials, 2022 - nature.com
Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging
depth and slow clearance from the body have impeded their use for in vivo disease …

Ultrasmall coinage metal nanoclusters as promising theranostic probes for biomedical applications

G Yang, Z Wang, F Du, F Jiang, X Yuan… - Journal of the American …, 2023 - ACS Publications
Ultrasmall coinage metal nanoclusters (NCs,< 3 nm) have emerged as a novel class of
theranostic probes due to their atomically precise size and engineered physicochemical …